Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CDC25B | P30305 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195278 | 0.85 | TSHR (0.75) | TSHRALDH1A1HSD17B10CDC25BCASP3 | |
| SCHEMBL29619268 | 0.85 | TSHR (0.75) | TSHRALDH1A1HSD17B10CDC25BCASP3 | |
| SCHEMBL15312370 | 0.84 | TSHR (0.61) | TSHRALDH1A1HSD17B10CDC25BSMN1; SMN2 | |
| SCHEMBL28151416 | 0.84 | MAPT (0.50) | ALDH1A1HSD17B10TDP1L3MBTL1KMT2A | |
| SCHEMBL9715928 | 0.83 | TSHR (0.61) | TSHRALDH1A1HSD17B10CDC25BCASP3 | |
| SCHEMBL30293099 | 0.83 | TSHR (0.61) | TSHRALDH1A1HSD17B10CDC25BCASP3 | |
| SCHEMBL7768843 | 0.82 | AKR1C3 (0.60) | ALDH1A1HSD17B10CDC25BPOLBKDM4E | |
| SCHEMBL13356584 | 0.81 | TSHR (0.62) | TSHRALDH1A1HSD17B10CDC25BCASP3 | |
| SCHEMBL28548575 | 0.81 | AKR1C3 (0.58) | ALDH1A1HSD17B10CDC25BPOLBKDM4E | |
| SCHEMBL11239143 | 0.81 | AKR1C3 (0.48) | ALDH1A1HSD17B10SMN1; SMN2POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280977-A1 | PROCESS FOR PREPARING CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L (IT) | 2009-11-12 | — | — | US | disclosed |
| EP-0849291-B1 | Catalyst for olefin polymerization and method for preparing polyolefins | JAPAN POLYOLEFINS CO LTD (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-6271167-B1 | TRIMETHOXYSILANE COMPOUND | JAPAN POLYOLEFINS CO., LTD. (JP) | 2001-08-07 | — | — | US | disclosed |
| EP-0717053-B1 | Catalyst for olefin polymerization and process for producing polyolefin using the same | JAPAN POLYOLEFINS CO LTD (JP) | 2001-03-14 | — | — | EP | disclosed |
| US-6121483-A | 3-alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin | SHOWA DENKO K.K. (JP) | 2000-09-19 | — | — | US | disclosed |
| US-6118019-A | 3-alkoxypropionic ester derivative | SHOWA DENKO K.K. (JP) | 2000-09-12 | — | — | US | disclosed |
| US-6096844-A | COMPRISING A TITANIUM COMPOUND, A MAGNESIUM COMPOUND, AND A HALOGEN COMPOUND, AN ORGANOALUMINUM COMPOUND, AN ORGANOSILICON COMPOUND | JAPAN POLYOLEFINS CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-6063727-A | CATALYSTS WHICH ENABLE EFFICIENT PRODUCTION OF POLYOLEFINS HAVING LOW MOLECULAR WEIGHT, BROAD MOLECULAR WEIGHT DISTRIBUTION, HIGH STEREOREGULARITY | JAPAN POLYOLEFINS CO., LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| US-6015867-A | MIXTURES OF ORGANOALUMINUM COMPOUNDS, MAGNESIUM, TITANIUM AND HALOGEN COMPOUNDS WITH ELECTRON DONOR ESTER AS INTENSIFIER, NONTOXIC, SAFE, EFFICIENT | SHOWA DENKO K.K. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0704424-B1 | 3-Alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin | SHOWA DENKO KK (JP) | 1998-12-30 | — | — | EP | disclosed |
| EP-0849291-A1 | Catalyst for olefin polymerization and method for preparing polyolefins | Japan Polyolefins Co., Ltd. (JP) | 1998-06-24 | — | — | EP | disclosed |
| US-5693729-A | STEREOSPECIFIC CATALYZING IN PRESENCE OF A MIXTURE CONSISTING OF A TITANIUM AND A MAGNESIUM COMPOUND, AN ORGANOALUMINUM COMPOUND OR AN ALUMOXANE, AN ORGANOSILICON COMPOUND | SHOWA DENKO K.K. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0578473-B1 | Catalyst for polymerization of olefin and process for producing olefin polymer | SHOWA DENKO KK (JP) | 1997-11-19 | — | — | EP | disclosed |
| EP-0640624-B1 | Catalyst for polymerization of olefin and process for the preparation of olefin polymer | SHOWA DENKO KK (JP) | 1997-06-18 | — | — | EP | disclosed |
| EP-0717053-A2 | Catalyst for olefin polymerization and process for producing polyolefin using the same | JAPAN POLYOLEFINS CO., LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |
| EP-0704424-A1 | 3-alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1996-04-03 | — | — | EP | disclosed |
| US-5476825-A | Consists of magnesium, titanium and halogen compounds, an organoaluminum compound, a reaction product of organoaluminum or organoboron compound with organosilicon compound | SHOWA DENKO K.K. (JP) | 1995-12-19 | — | — | US | disclosed |
| US-5407883-A | Containing magnesium, titanium, aluminum and silicon compounds including polymeric aluminum and alumoxanes | SHOWA DENKO K.K. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0640624-A1 | Catalyst for polymerization of olefin and process for the preparation of olefin polymer | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1995-03-01 | — | — | EP | disclosed |
| EP-0578473-A1 | Catalyst for polymerization of olefin and process for producing olefin polymer | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1994-01-12 | — | — | EP | disclosed |