SCHEMBL9715928

SCHEMBL9715928

CCOC(=O)c1cccc(C(=O)c2ccccc2)c1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.61
ALDH1A1 P00352 4/20 0.53
HSD17B10 Q99714 2/20 0.53
MAPT P10636 2/20 0.53
GAA P10253 1/20 0.53
CDC25B P30305 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.51
CASP3 P42574 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
HTT P42858 1/20 0.49
KDM4E B2RXH2 1/20 0.49
ALOX15 P16050 1/20 0.49
MAPK1 P28482 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29619268 0.87 TSHR (0.75) TSHRALDH1A1HSD17B10CDC25BL3MBTL1
SCHEMBL195278 0.87 TSHR (0.75) TSHRALDH1A1HSD17B10CDC25BL3MBTL1
SCHEMBL10571657 0.87 TSHR (0.73) TSHRALDH1A1HSD17B10MAPTGAA
SCHEMBL30293099 0.84 TSHR (0.61) TSHRALDH1A1HSD17B10MAPTGAA
SCHEMBL11052918 0.83 TSHR (0.63) TSHRALDH1A1HSD17B10MAPTGAA
SCHEMBL4463536 0.83 TSHR (0.59) TSHRALDH1A1HSD17B10MAPTGAA
SCHEMBL13356584 0.83 TSHR (0.62) TSHRALDH1A1HSD17B10MAPTGAA
SCHEMBL9631230 0.82 MAPT (0.57) TSHRALDH1A1HSD17B10MAPTGAA
Ammonia Solution, Strong SCHEMBL28460711 0.82 CA12 (0.63) TSHRALDH1A1HSD17B10MAPTGAA
SCHEMBL4239107 0.80 TSHR (0.63) TSHRALDH1A1HSD17B10MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0179303-B2 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Himont Incorporated (US) 1992-06-17 EP disclosed
EP-0179303-B1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Himont Incorporated (US) 1989-05-24 EP disclosed
EP-0086643-B1 CATALYST COMPOSITION AND PROCESS FOR POLYMERIZING OLEFINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-09-09 EP disclosed
EP-0086645-B1 CATALYST COMPOSITION AND PROCESS FOR POLYMERIZING OLEFINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1986-09-24 EP disclosed
EP-0179303-A1 Catalysts for the polymerization of olefins Himont Incorporated (US) 1986-04-30 EP disclosed
US-4529716-A Coordination catalyst MONTEDISON S.P.A. (IT) 1985-07-16 US disclosed
US-4473660-A COORDINATION CATALYST-CONTAINING ALKYL-ALUMINUM COMPOUND, ELECTRON DONOR, TITANIUM COMPOUND AND ESTER ON MAGNESIUM HALIDE SUPPORT MONTEDISON S.P.A. (IT) 1984-09-25 US disclosed
EP-0106141-A1 Catalyst components and catalysts for the polymerization of olefins Montedison S.p.A. (IT) 1984-04-25 EP disclosed
EP-0086645-A2 Catalyst composition and process for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-08-24 EP disclosed
EP-0086643-A2 Catalyst composition and process for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-08-24 EP disclosed