Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.51 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14321219 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4ESMN1; SMN2ALDH1A3ALDH3A1 | |
| SCHEMBL1609905 | 0.82 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL1609906 | 0.82 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL1611931 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2FBP1KMT2A | |
| SCHEMBL14321437 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2ALDH1A3APOBEC3A | |
| SCHEMBL12658705 | 0.80 | ITGB2 (0.45) | ALDH1A1KDM4ESMN1; SMN2APOBEC3AAPOBEC3G | |
| SCHEMBL14321448 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2FBP1KMT2A | |
| SCHEMBL1610377 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2ALDH1A3CRHBP | |
| SCHEMBL4082889 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2ALDH1A3KMT2A | |
| SCHEMBL14322049 | 0.77 | MAPT (0.55) | ALDH1A1KDM4ESMN1; SMN2ALDH1A3FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141096-A1 | SUBSTITUTED SPIRO-ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | WO | disclosed |