Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046202 | 0.81 | GRIA1 (0.48) | GRIA1GRIA3PDE4DMCL1GABRG2 | |
| SCHEMBL18411434 | 0.80 | GRIA1 (0.53) | GRIA1GRIA3PDE4DGABRG2GABRB3 | |
| SCHEMBL3475505 | 0.80 | GRIA1 (0.52) | GRIA1GRIA3PDE4DGABRG2GABRB3 | |
| SCHEMBL687843 | 0.80 | GRIA1 (0.58) | GRIA1GRIA3PDE4DMCL1CHEK1 | |
| SCHEMBL2925898 | 0.79 | GRIA1 (0.50) | GRIA1GRIA3PDE4DGABRG2GABRB3 | |
| SCHEMBL15758398 | 0.79 | GRIA1 (0.57) | GRIA1GRIA3PDE4DMCL1CHEK1 | |
| SCHEMBL18411316 | 0.79 | GRIA1 (0.52) | GRIA1GRIA3PDE4DGABRG2GABRB3 | |
| Water SCHEMBL4777578 | 0.76 | GRIA1 (0.56) | GRIA1GRIA3PDE4DGABRG2GABRB3 | |
| SCHEMBL4372512 | 0.76 | CHEK2 (0.42) | GRM5PRMT5WDR77 | |
| SCHEMBL2918046 | 0.76 | GRIA1 (0.56) | GRIA1GRIA3PDE4DGABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009054543-A1 | AMPA RECEPTOR ANTAGONISTS AND ZONISAMIDE FOR PARKINSON'S DISEASE AND MOVEMENT DISORDERS | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-04-30 | — | — | WO | disclosed |