SCHEMBL4464086

SCHEMBL4464086

COCCc1cc2c(cc1O)C1(CC2(C)C)CC(C)(C)c2cc(CCOC)c(O)cc21

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.34
HMGCR P04035 1/20 0.33
HCAR2 Q8TDS4 1/20 0.31
ESR1 P03372 1/20 0.31
CYP19A1 P11511 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4463972 0.92 POLB (0.31) POLB
SCHEMBL4464080 0.91 ESR1 (0.35) POLBHMGCRESR1CYP19A1ESR2
SCHEMBL4471806 0.83
SCHEMBL4459389 0.83 TSHR (0.35) HMGCRESR1
SCHEMBL4460505 0.83 HMGCR (0.42) POLBHMGCRESR1ESR2
SCHEMBL4454007 0.81 FTO (0.33)
SCHEMBL4474017 0.80 ESR1 (0.31) ESR1CYP19A1ESR2
SCHEMBL4471829 0.80 TYR (0.36) HMGCRESR1CYP19A1ESR2
SCHEMBL4462294 0.80 TYR (0.44) POLBHMGCRESR1CYP19A1ESR2
SCHEMBL4473836 0.79 CNR2 (0.38) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed