Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 18/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4461348 | 0.86 | GNRHR (0.75) | GNRHRKDM4ECYP2D6KMT2A | |
| SCHEMBL4468013 | 0.83 | GNRHR (1.00) | GNRHR | |
| SCHEMBL4460786 | 0.79 | GNRHR (0.75) | GNRHR | |
| SCHEMBL4471830 | 0.78 | GNRHR (0.78) | GNRHR | |
| SCHEMBL4482355 | 0.77 | GNRHR (0.56) | GNRHR | |
| SCHEMBL4463451 | 0.76 | GNRHR (0.75) | GNRHR | |
| SCHEMBL4461442 | 0.76 | GNRHR (0.75) | GNRHR | |
| SCHEMBL4465228 | 0.76 | GNRHR (0.77) | GNRHR | |
| SCHEMBL3278542 | 0.75 | GNRHR (0.78) | GNRHR | |
| SCHEMBL3278482 | 0.75 | GNRHR (0.76) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538113-B2 | 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-05-26 | — | — | US | claimed |
| US-20060189618-A1 | 4-Substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-08-24 | — | — | US | claimed |
| US-7538113-B2 | 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-05-26 | — | — | US | disclosed |
| US-20060189618-A1 | 4-Substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189618-A1 | 4-Substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | GNRHR, LHCGR, FSHR | GNRHR 1/4885KDM4E 657/4885CYP2D6 2877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.