⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29027947 | 0.94 | — | — | |
| SCHEMBL5622983 | 0.88 | FDPS (0.31) | — | |
| Hydrochloric Acid SCHEMBL9629122 | 0.85 | — | — | |
| SCHEMBL5132173 | 0.83 | FDPS (0.33) | — | |
| Hydrochloric Acid SCHEMBL18642429 | 0.81 | FDPS (0.32) | — | |
| SCHEMBL11805920 | 0.81 | GGPS1 (0.37) | — | |
| SCHEMBL3974451 | 0.81 | — | — | |
| SCHEMBL29027687 | 0.78 | FDPS (0.33) | — | |
| Hydrochloric Acid SCHEMBL28721766 | 0.78 | — | — | |
| SCHEMBL1248363 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184614-A | Substituted benzo five-membered unsaturated heterocyclic compounds, and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-06-14 | — | — | CN | disclosed |
| WO-2024119098-A1 | LIPID NANOPARTICLE (LNP) DELIVERY SYSTEMS AND FORMULATIONS | PRIME MEDICINE, INC. (US) | 2024-06-06 | — | — | WO | disclosed |
| CN-117279888-A | Compound or salt thereof, lipid particle and pharmaceutical composition | 富士胶片株式会社 | 2023-12-22 | — | — | CN | disclosed |
| EP-3298011-B1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | PRINCIPIA BIOPHARMA INC (US) | 2021-11-17 | — | — | EP | disclosed |
| US-20180155340-A1 | QUINOLONE DERIVATIVES AS FGFR INHIBITORS | PRINCIPIA BIOPHARMA INC. | 2018-06-07 | — | — | US | disclosed |
| US-7608618-B2 | Urea or thiourea substituted 1,4-pyrazine compounds useful as anti-cancer agents and for inhibiting Chk1 | ICOS CORPORATION (US) | 2009-10-27 | — | — | US | disclosed |