Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27961248 | 0.76 | ALDH1A1 (0.32) | SMN1; SMN2 | |
| SCHEMBL7819937 | 0.75 | ALDH1A1 (0.37) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27961251 | 0.75 | ALDH1A1 (0.31) | SMN1; SMN2 | |
| SCHEMBL27848372 | 0.73 | TSHR (0.32) | SMN1; SMN2 | |
| SCHEMBL7819425 | 0.72 | CYP19A1 (0.36) | SMN1; SMN2 | |
| SCHEMBL7817474 | 0.72 | ALDH1A1 (0.35) | SMN1; SMN2 | |
| SCHEMBL15286438 | 0.71 | KDM4E (0.35) | SMN1; SMN2 | |
| SCHEMBL28247088 | 0.71 | ALDH1A1 (0.32) | SMN1; SMN2 | |
| SCHEMBL28000517 | 0.71 | ALDH1A1 (0.32) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28132629 | 0.71 | ALDH1A1 (0.34) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049104-A2 | PYRROLIDINONE ANILINES AS PROGESTERONE RECEPTOR MODULATORS | SmithKline Beecham Corporation (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008021796-A2 | PYRROLIDINONE ANILINES AS PROGESTERONE RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |