Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 4/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855320 | 0.81 | LPAR1 (0.46) | PTPN11PTPROTHRATHRBLTB4R2 | |
| SCHEMBL13708345 | 0.73 | ACACB (0.40) | LPAR1LPAR2PPARD | |
| SCHEMBL5986339 | 0.72 | ACACB (0.41) | PTPN11PTPROTHRB | |
| SCHEMBL1735936 | 0.70 | STAT3 (0.80) | STAT3PTPN11PTPROPTGESALOX5 | |
| SCHEMBL1735945 | 0.69 | STAT3 (0.73) | STAT3PTPN11PTPROPTGESALOX5 | |
| SCHEMBL1734765 | 0.68 | STAT3 (0.66) | STAT3PTPN11PTPROPTGESALOX5 | |
| SCHEMBL2857128 | 0.67 | STAT3 (0.68) | STAT3PTPN11PTPROPTGESALOX5 | |
| SCHEMBL2858233 | 0.67 | ACACB (0.46) | THRATHRBLTB4R2LPAR1LPAR2 | |
| SCHEMBL2853433 | 0.66 | STAT3 (0.75) | STAT3PTPN11PTPROPTGESALOX5 | |
| SCHEMBL1736183 | 0.66 | STAT3 (0.60) | STAT3PTPN11PTPRO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589232-B2 | Alkynyl aryl carboxamides | LABORATORIES SERONO S.A. (CH) | 2009-09-15 | — | — | US | claimed |