Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855320 | 0.89 | LPAR1 (0.46) | TP53MAPTPOLBPTPN11PTPRO | |
| SCHEMBL13708345 | 0.87 | ACACB (0.40) | ACACBTP53MAPTPOLB | |
| SCHEMBL5497713 | 0.76 | THRB (0.46) | ACACBPTPN11PTPROTHRB | |
| SCHEMBL5507735 | 0.76 | PTGES (0.54) | ACACBPTPN11PTPROTHRB | |
| SCHEMBL2853046 | 0.74 | THRB (0.45) | ACACBPTPN11PTPROTHRB | |
| SCHEMBL2858233 | 0.73 | ACACB (0.46) | ACACBTHRB | |
| SCHEMBL4055579 | 0.72 | THRB (0.55) | ACACBTHRB | |
| SCHEMBL4464485 | 0.72 | STAT3 (0.42) | PTPN11PTPROTHRB | |
| SCHEMBL1415501 | 0.72 | THRB (0.61) | POLBTHRB | |
| SCHEMBL5501954 | 0.72 | PSMB5 (0.44) | ACACBMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654247-A1 | ALKYNYL ARYL CARBOXAMIDES | Applied Research Systems ARS Holding N.V. (AN) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005012280-A1 | ALKYNYL ARYL CARBOXAMIDES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-02-10 | — | — | WO | disclosed |