Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459963 | 0.84 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1CYP3A4ACACB | |
| SCHEMBL7719250 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMHTTALDH1A1CYP3A4 | |
| SCHEMBL13645867 | 0.79 | HTT (0.46) | SMN1; SMN2PKMHTTALDH1A1CYP3A4 | |
| SCHEMBL13645758 | 0.77 | HTT (0.44) | SMN1; SMN2PKMHTTALDH1A1CYP3A4 | |
| SCHEMBL6592513 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2PKMHTTALDH1A1CYP3A4 | |
| SCHEMBL4456772 | 0.72 | MAPT (0.52) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL221191 | 0.72 | MAPT (0.52) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL221192 | 0.72 | MAPT (0.52) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL11124472 | 0.71 | PPID (0.44) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL11124469 | 0.71 | PPID (0.44) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |