SCHEMBL4464897

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4474048	0.82	EPHB4 (1.00)	EPHB4KDRBRAF
	Gw856804X SCHEMBL4471490	0.81	EPHB4 (1.00)	EPHB4KDRBRAFAURKAROCK2
	Gw856804X SCHEMBL32678604	0.81	EPHB4 (1.00)	EPHB4KDRBRAFAURKAROCK2
	Gw856804X SCHEMBL32678600	0.81	EPHB4 (1.00)	EPHB4KDRBRAFAURKAROCK2
	Gw856804X SCHEMBL32678602	0.81	EPHB4 (1.00)	EPHB4KDRBRAFAURKAROCK2
	SCHEMBL4461110	0.80	EPHB4 (0.71)	EPHB4KDRBRAFBTKAURKA
	SCHEMBL4473188	0.80	EPHB4 (1.00)	EPHB4KDRBRAFAURKAROCK2
	SCHEMBL4467257	0.79	EPHB4 (1.00)	EPHB4KDRBRAFAURKAROCK2
	SCHEMBL13708295	0.78	EPHB4 (0.68)	EPHB4KDRBRAFAURKAROCK2
	SCHEMBL4472583	0.77	EPHB4 (1.00)	EPHB4KDRBRAFBTKAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.