Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | FBP1 | P09467 | 1/20 | 0.57 |
| ▸ | ACP1 | P24666 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922237 | 0.91 | MEN1 (0.59) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL9920076 | 0.90 | MEN1 (0.57) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL9424721 | 0.88 | MAPT (0.58) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL1547882 | 0.87 | MAPT (0.54) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL9920082 | 0.86 | KMT2A (0.60) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL1548436 | 0.82 | SCN2A (0.50) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL1548077 | 0.81 | MAPT (0.54) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL9923098 | 0.79 | P2RY12 (0.45) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL9920074 | 0.79 | POLB (0.45) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL9922955 | 0.79 | FBP1 (0.47) | LMNASMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067607-A2 | COMBINATIONS OF PDE4 INHIBITORS AND ANTIPSYCHOTICS FOR THE TREATMENT OF PSYCHOTIC DISORDERS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2009-05-28 | — | — | WO | disclosed |