SCHEMBL4465697

SCHEMBL4465697

C=CCCCCCCCCCCCO[Si](C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
LPAR3 Q9UBY5 2/20 0.44
LPAR2 Q9HBW0 1/20 0.44
ALDH1A1 P00352 5/20 0.39
LMNA P02545 3/20 0.39
SLC2A1 P11166 1/20 0.37
MAPT P10636 2/20 0.35
ABCC4 O15439 1/20 0.35
TRPA1 O75762 1/20 0.33
USP2 O75604 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
HPGD P15428 1/20 0.32
CYP3A4 P08684 2/20 0.32
ADORA1 P30542 1/20 0.32
CDK1 P06493 1/20 0.32
CCNB1 P14635 1/20 0.32
CCNA2 P20248 1/20 0.32
CDK2 P24941 1/20 0.32
CCNA1 P78396 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4462375 1.00 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL817880 1.00 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL2864503 1.00 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL4457155 1.00 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL4460489 1.00 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL4464834 1.00 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL817724 1.00 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL4453485 0.98 TSHR (0.42) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL4461104 0.91 TSHR (0.42) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL8898479 0.86 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7479531-B2 Copolymer of ethylene and/or propylene; and octen-1-ol,7-octen-1-ol trimethylsilyl ether, octenyl acetate, 5-norbornen-2-yl acetate, 5-norbornen-2-ol and/or 5-norbornen-2-ol trimethylsilyl ether; transition metal catalyst comprising 2-arylazo- or 2-arylphosphazo- phenoxide ligand EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-01-20 US claimed
US-7285609-B2 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-23 US claimed
EP-1626999-B1 OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS EXXONMOBIL CHEM PATENTS INC (US) 2007-09-26 EP claimed
US-20070197751-A1 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. 2007-08-23 US claimed
EP-1626999-A1 OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS Exxonmobil Chemical Patents Inc. (US) 2006-02-22 EP claimed
US-20040260043-A1 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS, INC. 2004-12-23 US claimed
WO-2004101634-A1 OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-11-25 WO claimed
US-7479531-B2 Copolymer of ethylene and/or propylene; and octen-1-ol,7-octen-1-ol trimethylsilyl ether, octenyl acetate, 5-norbornen-2-yl acetate, 5-norbornen-2-ol and/or 5-norbornen-2-ol trimethylsilyl ether; transition metal catalyst comprising 2-arylazo- or 2-arylphosphazo- phenoxide ligand EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-01-20 US disclosed
US-7285609-B2 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-23 US disclosed
EP-1626999-B1 OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS EXXONMOBIL CHEM PATENTS INC (US) 2007-09-26 EP disclosed
US-20070197751-A1 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. 2007-08-23 US disclosed
EP-1626999-A1 OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS Exxonmobil Chemical Patents Inc. (US) 2006-02-22 EP disclosed
US-20040260043-A1 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS, INC. 2004-12-23 US disclosed
WO-2004101634-A1 OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-11-25 WO disclosed