SCHEMBL817880

SCHEMBL817880

C=CCCCCCCCCCO[Si](C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
LPAR3 Q9UBY5 2/20 0.44
LPAR2 Q9HBW0 1/20 0.44
ALDH1A1 P00352 5/20 0.39
LMNA P02545 3/20 0.39
SLC2A1 P11166 1/20 0.37
MAPT P10636 2/20 0.35
ABCC4 O15439 1/20 0.35
TRPA1 O75762 1/20 0.33
USP2 O75604 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
HPGD P15428 1/20 0.32
CYP3A4 P08684 2/20 0.32
ADORA1 P30542 1/20 0.32
CDK1 P06493 1/20 0.32
CCNB1 P14635 1/20 0.32
CCNA2 P20248 1/20 0.32
CDK2 P24941 1/20 0.32
CCNA1 P78396 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4462375 1.00 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL2864503 1.00 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL4457155 1.00 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL4460489 1.00 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL4464834 1.00 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL817724 1.00 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL4465697 1.00 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL4453485 0.98 TSHR (0.42) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL4461104 0.91 TSHR (0.42) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL8898479 0.86 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115572341-B Functionalized polyolefin elastomer and preparation method thereof 大连万慷工业科技有限公司 2024-04-23 CN claimed
US-7479531-B2 Copolymer of ethylene and/or propylene; and octen-1-ol,7-octen-1-ol trimethylsilyl ether, octenyl acetate, 5-norbornen-2-yl acetate, 5-norbornen-2-ol and/or 5-norbornen-2-ol trimethylsilyl ether; transition metal catalyst comprising 2-arylazo- or 2-arylphosphazo- phenoxide ligand EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-01-20 US claimed
US-7285609-B2 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-23 US claimed
EP-1626999-B1 OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS EXXONMOBIL CHEM PATENTS INC (US) 2007-09-26 EP claimed
US-20070197751-A1 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. 2007-08-23 US claimed
EP-1626999-A1 OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS Exxonmobil Chemical Patents Inc. (US) 2006-02-22 EP claimed
US-20040260043-A1 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS, INC. 2004-12-23 US claimed
WO-2004101634-A1 OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-11-25 WO claimed
EP-4608926-A1 HOT MELT ADHESIVE COMPRISING SILOXIDE-FUNCTIONALIZED POLYOLEFINS SABIC Global Technologies B.V. (NL) 2025-09-03 EP disclosed
US-12286496-B2 Functional polyolefin polymers and manufacture thereof ADVANCED POLYOLEFIN TECHNOLOGIES LLC (US) 2025-04-29 US disclosed
WO-2025002626-A1 HOT MELT ADHESIVES BASED ON BLENDS COMPRISING NON- FUNCTIONALIZED AND FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-01-02 WO disclosed
WO-2025002627-A1 HOT MELT ADHESIVES BASED ON BLENDS COMPRISING NON-FUNCTIONALIZED AND FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-01-02 WO disclosed
CN-115572341-B Functionalized polyolefin elastomer and preparation method thereof 大连万慷工业科技有限公司 2024-04-23 CN disclosed
US-20240076432-A1 FUNCTIONAL POLYOLEFIN POLYMERS AND MANUFACTURE THEREOF ADVANCED POLYOLEFIN TECHNOLOGIES LLC 2024-03-07 US disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed
US-5527935-A Organopolysiloxanes having bifunctional terminal siloxane units WACKER-CHEMIE GMBH (DE) 1996-06-18 US disclosed
EP-0623149-A4 POLYMERIZATION OF FUNCTIONALIZED MONOMERS WITH ZIEGLER-NATTA CATALYSTS. UNIV LELAND STANFORD JUNIOR (US) 1995-09-27 EP disclosed
EP-0646616-A1 Organopolysiloxanes having bifunctional siloxane end groups Wacker-Chemie GmbH (DE) 1995-04-05 EP disclosed
EP-0623149-A1 POLYMERIZATION OF FUNCTIONALIZED MONOMERS WITH ZIEGLER-NATTA CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1994-11-09 EP disclosed
WO-1994012547-A2 POLYMERIZATION OF FUNCTIONALIZED MONOMERS WITH ZIEGLER-NATTA CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1994-06-09 WO disclosed