Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.61 |
| ▸ | TNKS | O95271 | 5/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.53 |
| ▸ | PARP1 | P09874 | 4/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237120 | 0.85 | TRPV1 (0.56) | TNKSTNKS2TRPV1NPBWR1DGAT1 | |
| SCHEMBL4195594 | 0.81 | NPC1 (0.53) | TNKSTNKS2PARP1KDM4EALDH1A1 | |
| SCHEMBL2668125 | 0.80 | NPC1 (0.56) | TNKSTNKS2PARP1KDM4EALDH1A1 | |
| SCHEMBL5320202 | 0.80 | NPC1 (0.40) | HDAC6TNKSTNKS2TRPV1PARP1 | |
| SCHEMBL6245186 | 0.80 | MAPT (0.58) | TNKSTNKS2PARP1KDM4EALDH1A1 | |
| SCHEMBL9692278 | 0.80 | KDM4E (0.54) | TNKSTNKS2KDM4EALDH1A1KMT2A | |
| SCHEMBL9975911 | 0.80 | HPSE (0.41) | TNKSTNKS2PARP1KDM4EALDH1A1 | |
| Methane SCHEMBL9692076 | 0.78 | KDM4E (0.53) | TNKSTNKS2KDM4EALDH1A1KMT2A | |
| SCHEMBL15633796 | 0.78 | NPC1 (0.46) | PARP1KDM4EALDH1A1KMT2AMETAP2 | |
| SCHEMBL6755306 | 0.76 | HDAC6 (1.00) | HDAC6TNKSTNKS2TRPV1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538113-B2 | 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-05-26 | — | — | US | disclosed |
| US-20060189618-A1 | 4-Substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189618-A1 | 4-Substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | GNRHR, LHCGR, FSHR | HDAC6 1529/4885TNKS 2751/4885TNKS2 3420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.