Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4466165 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HPGDCYP2C19NPC1RAB9A | |
| SCHEMBL4466167 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HPGDCYP2C19NPC1RAB9A | |
| SCHEMBL4466177 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HPGDCYP2C19NPC1RAB9A | |
| SCHEMBL4466172 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HPGDCYP2C19NPC1RAB9A | |
| SCHEMBL9046361 | 0.88 | CYP3A4 (0.44) | ALDH1A1HPGDKDM4EAKR1C3CYP3A4 | |
| SCHEMBL9046349 | 0.88 | CYP3A4 (0.44) | ALDH1A1HPGDKDM4EAKR1C3CYP3A4 | |
| SCHEMBL9046355 | 0.88 | CYP3A4 (0.44) | ALDH1A1HPGDKDM4EAKR1C3CYP3A4 | |
| SCHEMBL9046398 | 0.88 | CYP3A4 (0.44) | ALDH1A1HPGDKDM4EAKR1C3CYP3A4 | |
| SCHEMBL9046368 | 0.88 | CYP3A4 (0.44) | ALDH1A1HPGDKDM4EAKR1C3CYP3A4 | |
| SCHEMBL9045993 | 0.88 | ALDH1A1 (0.40) | ALDH1A1HPGDCYP2C19NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | claimed |
| EP-1931359-A4 | COMBINATION THERAPY FOR CONTROLLED CARBOHYDRATE DIGESTION | ELIXIR PHARMACEUTICALS INC (US) | 2009-04-01 | — | — | EP | disclosed |
| EP-1931359-A2 | COMBINATION THERAPY FOR CONTROLLED CARBOHYDRATE DIGESTION | Elixir Pharmaceuticals, Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007033292-A2 | COMBINATION THERAPY FOR CONTROLLED CARBOHYDRATE DIGESTION | ELIXIR PHARMACEUTICALS, INC. (US) | 2007-03-22 | — | — | WO | disclosed |
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |