Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | S100A4 | P26447 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL768880 | 0.83 | MAPT (0.53) | MAPTS100A4RECQLKMT2AMCL1 | |
| SCHEMBL2214434 | 0.80 | MAPT (0.43) | MAPTS100A4RECQLKMT2AMCL1 | |
| SCHEMBL4573599 | 0.79 | MAPT (0.53) | MAPTS100A4RECQLKMT2AMCL1 | |
| SCHEMBL4659345 | 0.76 | MAPT (0.43) | MAPTS100A4RECQLKMT2AMCL1 | |
| SCHEMBL35211484 | 0.75 | MAPT (0.56) | MAPTS100A4RECQLKMT2AMCL1 | |
| SCHEMBL166701 | 0.75 | MAPT (0.56) | MAPTS100A4RECQLKMT2AMCL1 | |
| SCHEMBL31207333 | 0.75 | MEN1 (0.48) | MAPTKMT2ATDP1TSHRALDH1A1 | |
| SCHEMBL2243721 | 0.75 | MEN1 (0.48) | MAPTKMT2ATDP1TSHRALDH1A1 | |
| SCHEMBL18329006 | 0.74 | MAPT (0.47) | MAPTS100A4RECQLKMT2AMCL1 | |
| SCHEMBL16445689 | 0.72 | ALDH1A1 (0.47) | MAPTS100A4RECQLKMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141096-A1 | SUBSTITUTED SPIRO-ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | WO | disclosed |