Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4466573 | 1.00 | F10 (0.45) | F10CTSLCTSBCTSSHTT | |
| SCHEMBL4458558 | 0.98 | F10 (0.45) | F10CTSLCTSBCTSS | |
| SCHEMBL4458555 | 0.98 | F10 (0.45) | F10CTSLCTSBCTSS | |
| SCHEMBL4479439 | 0.93 | F10 (0.41) | F10CTSLCTSBCTSSHTT | |
| SCHEMBL4466970 | 0.93 | F10 (0.46) | F10HTT | |
| SCHEMBL4466966 | 0.93 | F10 (0.46) | F10HTT | |
| SCHEMBL4475663 | 0.93 | F10 (0.44) | F10HTT | |
| SCHEMBL4475661 | 0.93 | F10 (0.44) | F10HTT | |
| SCHEMBL4472269 | 0.92 | F10 (0.41) | F10CTSLCTSBCTSSHTT | |
| SCHEMBL4459695 | 0.92 | F10 (0.45) | F10CTSLCTSBCTSSHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476663-B2 | Substituted thiophene carboxamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-01-13 | — | — | US | disclosed |
| US-20050277628-A1 | Substituted thiophene carboxamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277628-A1 | Substituted thiophene carboxamides | OTC, SLC22A8, DDC | F10 2132/4885CTSL 4233/4885CTSB 4029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.