Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15116635 | 0.86 | PKM (0.51) | PKMMAPK1SMN1; SMN2PDK1ALDH1A1 | |
| SCHEMBL15106278 | 0.84 | PKM (0.53) | PKMMAPK1SMN1; SMN2PDK1ALDH1A1 | |
| SCHEMBL3892811 | 0.84 | PKM (0.53) | PKMMAPK1SMN1; SMN2PDK1ALDH1A1 | |
| SCHEMBL15106276 | 0.84 | PKM (0.53) | PKMMAPK1SMN1; SMN2PDK1ALDH1A1 | |
| SCHEMBL15106275 | 0.84 | PKM (0.53) | PKMMAPK1SMN1; SMN2PDK1ALDH1A1 | |
| SCHEMBL10233923 | 0.83 | PKM (0.49) | PKMMAPK1SMN1; SMN2PDK1ALDH1A1 | |
| SCHEMBL18478123 | 0.81 | SMN1; SMN2 (0.52) | PKMMAPK1SMN1; SMN2PDK1ALDH1A1 | |
| SCHEMBL1196644 | 0.81 | SMN1; SMN2 (0.52) | PKMMAPK1SMN1; SMN2PDK1ALDH1A1 | |
| SCHEMBL20671801 | 0.81 | SMN1; SMN2 (0.52) | PKMMAPK1SMN1; SMN2PDK1ALDH1A1 | |
| SCHEMBL4000982 | 0.81 | SMN1; SMN2 (0.52) | PKMMAPK1SMN1; SMN2PDK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |