⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL751581 | 0.71 | HDAC8 (0.33) | — | |
| SCHEMBL8490083 | 0.67 | — | — | |
| SCHEMBL1429 | 0.67 | — | — | |
| SCHEMBL5908051 | 0.67 | — | — | |
| SCHEMBL449154 | 0.67 | — | — | |
| SCHEMBL164914 | 0.67 | — | — | |
| SCHEMBL5042962 | 0.67 | — | — | |
| SCHEMBL27545 | 0.67 | — | — | |
| SCHEMBL1766590 | 0.67 | — | — | |
| SCHEMBL59532 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3946431-A1 | MODIFIED HEMOGLOBIN MOLECULES AND USES THEREOF | University of Pittsburgh - of the Commonwealth System of Higher Education (US) | 2022-02-09 | — | — | EP | claimed |
| CN-113811323-A | Modified hemoglobin molecules and uses thereof | 高等教育联邦系统-匹兹堡大学 | 2021-12-17 | — | — | CN | claimed |
| WO-2020206159-A1 | MODIFIED HEMOGLOBIN MOLECULES AND USES THEREOF | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-10-08 | — | — | WO | claimed |
| CN-110746407-A | Amide derivative containing benzimidazole group, preparation method and application thereof | 南京农业大学 | 2020-02-04 | — | — | CN | claimed |
| EP-0306943-B1 | Immunconjugates joined by thioether bonds having reduced toxicity and improved selectivity | NEORX CORP (US) | 1994-11-30 | — | — | EP | claimed |
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | claimed |
| US-4981979-A | IMMUNOLOGY | NEORX CORPORATION (US) | 1991-01-01 | — | — | US | claimed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | claimed |
| EP-0306943-A2 | Immunconjugates joined by thioether bonds having reduced toxicity and improved selectivity | NEORX CORPORATION (US) | 1989-03-15 | — | — | EP | claimed |
| CN-110891611-B | Hydrogel crosslinked hyaluronic acid prodrug compositions and methods | 阿森迪斯制药公司 | 2024-03-29 | — | — | CN | disclosed |
| US-20230414770-A1 | HYDROGEL CROSS-LINKED HYALURONIC ACID PRODRUG COMPOSITIONS AND METHODS | ASCENDIS PHARMA A/S (DK) | 2023-12-28 | — | — | US | disclosed |
| US-11642415-B2 | Hydrogel cross-linked hyaluronic acid prodrug compositions and methods | ASCENDIS PHARMA A/S (DK) | 2023-05-09 | — | — | US | disclosed |
| EP-3438118-B1 | PEPTIDE DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES (JP) | 2023-03-29 | — | — | EP | disclosed |
| US-20220185867-A1 | MODIFIED HEMOGLOBIN MOLECULES AND USES THEREOF | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-06-16 | — | — | US | disclosed |
| EP-0058434-A1 | N-2-hydroxypropyl piperidines and process for preparing the same | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1982-08-25 | — | — | EP | disclosed |
| US-4336183-A | 2,2,6,6-Tetramethyl-4-piperidyl carboxylic acid esters and amides of mono and poly alcohols, phenols and amines as stabilizers for synthetic polymers | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1982-06-22 | — | — | US | disclosed |
| US-4312804-A | HEAT RESISTANCE, ULTRAVIOLET RADIATION RESISTANCE | ARGUS CHEMICAL CORPORATION (US) | 1982-01-26 | — | — | US | disclosed |
| EP-0023330-A1 | 2,2,6,6-Tetraalkyl-4-piperidyl alcohol esters of tetradecylene polycarboxylic acids as light stabilizers for synthetic polymers and stabilized compositions | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1981-02-04 | — | — | EP | disclosed |
| EP-0022997-A1 | 2,2,6,6-Tetramethyl-4-piperidyl carboxylic acid esters and amides of mono and poly alcohols, phenols and amines and synthetic polymer compositions stabilized thereby | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1981-01-28 | — | — | EP | disclosed |
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |