⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL751581 | 0.71 | HDAC8 (0.33) | — | |
| SCHEMBL4029055 | 0.67 | — | — | |
| SCHEMBL449154 | 0.67 | — | — | |
| SCHEMBL4466845 | 0.67 | — | — | |
| SCHEMBL164914 | 0.67 | — | — | |
| SCHEMBL1766590 | 0.67 | — | — | |
| SCHEMBL1429 | 0.67 | — | — | |
| SCHEMBL5042962 | 0.67 | — | — | |
| SCHEMBL5908051 | 0.67 | — | — | |
| SCHEMBL27545 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3731 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239755-A1 | SUBSTITUTED PYRIDAZINONES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-07-18 | — | — | US | claimed |
| CN-118290434-A | Spiropiperidine derivative containing alpha-methylene-gamma-butyrolactone, preparation method and application thereof | 南开大学 | 2024-07-05 | — | — | CN | claimed |
| CN-118240807-A | Nitrilase mutant with improved heat stability and application thereof in synthesis of 2-chloronicotinic acid | 浙江工业大学 | 2024-06-25 | — | — | CN | claimed |
| CN-115477615-B | N- (3- (benzimidazol-2-yl) phenyl) amide compound and preparation method and application thereof | 黄山学院 | 2024-06-18 | — | — | CN | claimed |
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | claimed |
| EP-4373825-A1 | NITRILE SUMO INHIBITORS AND USES THEREOF | Suvalent Therapeutics, Inc. (US) | 2024-05-29 | — | — | EP | claimed |
| CN-117778359-A | Nitrilase mutant and method for biocatalysis co-production of chloronicotinic acid | 浙江工业大学 | 2024-03-29 | — | — | CN | claimed |
| EP-4330234-A1 | SUBSTITUTED PYRIDAZINONES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-03-06 | — | — | EP | claimed |
| CN-117603950-A | Nitrilase mutant and application thereof in catalytic synthesis of 2-chloronicotinic acid | 浙江工业大学 | 2024-02-27 | — | — | CN | claimed |
| WO-2024022362-A1 | FUSED RING COMPOUND WITH SULFUR-CONTAINING SUBSTITUENT, PREPARATION METHOD, INSECTICIDE COMPOSITION, AND USE | 江苏中旗科技股份有限公司 | 2024-02-01 | — | — | WO | claimed |
| US-4654353-A | ANTIISCHEMIC | PFIZER INC. (US) | 1987-03-31 | — | — | US | claimed |
| EP-0200524-A2 | Dihydropyridine calcium antagonists | Pfizer Limited (GB) | 1986-11-05 | — | — | EP | claimed |
| EP-0161917-A2 | Dihydropyridines | Pfizer Limited (GB) | 1985-11-21 | — | — | EP | claimed |
| US-4340739-A | CHEMICAL INTERMEDIATES IN THE PRODUCTION OF N-AZOLYLMETHYL-COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1982-07-20 | — | — | US | claimed |
| EP-0005911-B1 | ANALGESIC 6-ACYLAMINOTETRAHYDRO-1,3,5-TRIAZINE-2,4-DIONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND PROCESS FOR THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-02-17 | — | — | EP | claimed |
| US-4269842-A | Method for treating rhinoviral complaints | RHONE-POULENC INDUSTRIES (FR) | 1981-05-26 | — | — | US | claimed |
| US-4254122-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ENZYME INHIBITORS OF PROSTAGLANDIN SYNTHETASE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-03-03 | — | — | US | claimed |
| US-4252957-A | GALLSTONE SOLVENTS | PFIZER INC. (US) | 1981-02-24 | — | — | US | claimed |
| US-4226738-A | SUPERIOR LIGHT INTENSITY, QUANTUM EFFICIENT, AND LONG-LASTING | AMERICAN CYANAMID COMPANY (US) | 1980-10-07 | — | — | US | claimed |
| US-4163784-A | ACYLUREA DERIVATIVES | PFIZER INC. (US) | 1979-08-07 | — | — | US | claimed |