Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 12/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4470201 | 0.89 | MAPK14 (0.39) | DGAT2MAPK14SCN9ATP53MAPK13 | |
| SCHEMBL5113184 | 0.83 | SCN9A (0.39) | MAPK14SCN9AMAPK13MAPK12MAPK11 | |
| SCHEMBL4473486 | 0.81 | MAPK14 (0.43) | DGAT2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4470456 | 0.81 | MAPK14 (0.42) | MAPK14SCN9AMAPK13MAPK12MAPK11 | |
| SCHEMBL4463178 | 0.81 | MAPK14 (0.46) | MAPK14SCN9AMAPK13MAPK12MAPK11 | |
| SCHEMBL3228338 | 0.81 | MAT2A (0.39) | DGAT2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL1061169 | 0.78 | MAPK14 (0.40) | MAPK14SCN9AMAPK13MAPK12MAPK11 | |
| SCHEMBL1060462 | 0.77 | SCN9A (0.37) | MAPK14SCN9AMAPK13MAPK12MAPK11 | |
| Dilmapimod SCHEMBL1065268 | 0.77 | MAPK14 (0.47) | MAPK14SCN9AMAPK13MAPK12MAPK11 | |
| SCHEMBL4473445 | 0.77 | MAPK14 (0.45) | MAPK14SCN9AMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629350-B2 | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-08 | — | — | US | disclosed |