Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.49 |
| ▸ | BTK | Q06187 | 11/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.39 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128439 | 0.89 | GPR119 (0.56) | CYP3A4GPR119 | |
| SCHEMBL1128995 | 0.85 | CYP3A4 (0.48) | CYP3A4GPR119BTKLCKNUDT14 | |
| SCHEMBL2019784 | 0.82 | CYP3A4 (0.79) | CYP3A4GPR119 | |
| SCHEMBL27755048 | 0.77 | GPR119 (0.58) | CYP3A4GPR119PIK3CD | |
| SCHEMBL9006352 | 0.75 | CYP3A4 (0.79) | CYP3A4GPR119 | |
| SCHEMBL1128844 | 0.74 | CYP3A4 (0.84) | CYP3A4GPR119 | |
| SCHEMBL1128328 | 0.74 | CYP3A4 (0.80) | CYP3A4GPR119 | |
| SCHEMBL2022044 | 0.74 | CYP3A4 (0.57) | CYP3A4GPR119PIK3CD | |
| SCHEMBL1450363 | 0.73 | CYP3A4 (0.47) | CYP3A4GPR119BTK | |
| SCHEMBL1128434 | 0.73 | CYP3A4 (0.73) | CYP3A4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141238-A1 | GPR119 RECEPTOR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-11-26 | — | — | WO | disclosed |