⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214566 | 0.74 | MCL1 (0.30) | — | |
| SCHEMBL2891916 | 0.72 | — | — | |
| SCHEMBL2486612 | 0.69 | — | — | |
| SCHEMBL8906773 | 0.69 | — | — | |
| SCHEMBL28190818 | 0.69 | — | — | |
| SCHEMBL2410413 | 0.69 | — | — | |
| SCHEMBL62916 | 0.69 | — | — | |
| SCHEMBL23733932 | 0.67 | — | — | |
| SCHEMBL9733633 | 0.67 | — | — | |
| SCHEMBL9483414 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11142545-B2 | Synthesis of thiolated oligonucleotides without a capping step | BIOGEN MA INC. (US) | 2021-10-12 | — | — | US | disclosed |
| US-20190161513-A1 | SYNTHESIS OF THIOLATED OLIGONUCLEOTIDES WITHOUT A CAPPING STEP | BIOGEN MA INC. | 2019-05-30 | — | — | US | disclosed |
| EP-3475292-A1 | SYNTHESIS OF THIOLATED OLIGONUCLEOTIDES WITHOUT A CAPPING STEP | Biogen MA Inc. (US) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017223258-A1 | SYNTHESIS OF THIOLATED OLIGONUCLEOTIDES WITHOUT A CAPPING STEP | BIOGEN MA INC. (US) | 2017-12-28 | — | — | WO | disclosed |
| EP-2266958-B1 | Antiviral agent | SHIONOGI & CO (JP) | 2017-03-15 | — | — | EP | disclosed |
| US-7605154-B2 | ATP-protein kinase inhibitors; cytomegalovirus; contraceptive agents; cancer; N7-(3-ethynyl-phenyl)-N2-(4-piperidin-1-ylmethyl-phenyl)-thiazolo[4,5-d]pyrimidine-2,7-diamine | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-10-20 | — | — | US | disclosed |
| CN-100384837-C | Farnesyl protein transferase inhibitors as antitumor agents | SCHERING CORP (US) | 2008-04-30 | — | — | CN | disclosed |
| EP-1912639-A2 | THIAZOLOPYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-23 | — | — | EP | disclosed |
| US-20070185139-A1 | Thiazolopyrimidine kinase inhibitors | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-08-09 | — | — | US | disclosed |
| WO-2007019191-A2 | THIAZOLOPYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-02-15 | — | — | WO | disclosed |
| US-4502882-A | HERBICIDES, PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-03-05 | — | — | US | disclosed |
| US-4465506-A | Herbicidal N-[heterocyclicaminocarbonyl]-1H-indene and tetrahydronaphthalene sulfonamides | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1984-08-14 | — | — | US | disclosed |
| US-4421550-A | PRE- AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-12-20 | — | — | US | disclosed |
| EP-0051067-A1 | TRIAZINE SYNTHESIS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1982-05-12 | — | — | EP | disclosed |
| EP-0051067-A1 | TRIAZINE SYNTHESIS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1982-05-12 | — | — | EP | disclosed |
| EP-0001699-B1 | DERIVATIVES OF FURYL COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1982-02-24 | — | — | EP | disclosed |
| WO-1981003020-A1 | TRIAZINE SYNTHESIS | COMMW SCIENT IND RES ORG (AU) | 1981-10-29 | — | — | WO | disclosed |
| WO-1981003020-A1 | TRIAZINE SYNTHESIS | COMMW SCIENT IND RES ORG (AU) | 1981-10-29 | — | — | WO | disclosed |
| US-4288443-A | HISTAMINE ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1981-09-08 | — | — | US | disclosed |
| EP-0001699-A2 | Derivatives of furyl compounds, their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1979-05-02 | — | — | EP | disclosed |