Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892014 | 0.87 | KDM4E (0.39) | L3MBTL1HTTATMPOLBKDM4E | |
| SCHEMBL1645689 | 0.81 | POLB (0.34) | L3MBTL1HTTATMPOLBKDM4E | |
| SCHEMBL1645335 | 0.80 | SMN1; SMN2 (0.45) | L3MBTL1HTTPOLBKDM4ERAB9A | |
| SCHEMBL1645957 | 0.74 | GAA (0.40) | L3MBTL1HTTATMPOLBKDM4E | |
| SCHEMBL1645505 | 0.67 | SMN1; SMN2 (0.39) | L3MBTL1HTTPOLBKDM4ERAB9A | |
| SCHEMBL1645503 | 0.67 | SMN1; SMN2 (0.39) | L3MBTL1HTTPOLBKDM4ERAB9A | |
| SCHEMBL4440012 | 0.67 | SMN1; SMN2 (0.44) | L3MBTL1HTTPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL17397156 | 0.67 | KDM4E (0.35) | KDM4ERAB9ASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL17397181 | 0.64 | KDM4E (0.39) | L3MBTL1HTTKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL7169839 | 0.60 | KDM4E (0.37) | HTTPOLBKDM4EMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144473-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |