Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4467335 | 0.87 | L3MBTL1 (0.38) | KDM4ERAB9ASMN1; SMN2L3MBTL1HTT | |
| SCHEMBL1645957 | 0.77 | GAA (0.40) | KDM4ERAB9ASMN1; SMN2L3MBTL1HTT | |
| SCHEMBL1520638 | 0.73 | L3MBTL1 (0.67) | KDM4ERAB9ASMN1; SMN2L3MBTL1HTT | |
| SCHEMBL4440012 | 0.70 | SMN1; SMN2 (0.44) | KDM4ESMN1; SMN2L3MBTL1HTTPOLB | |
| SCHEMBL29142660 | 0.68 | KDM4E (0.38) | KDM4ERAB9ASMN1; SMN2L3MBTL1HTT | |
| SCHEMBL1646251 | 0.66 | L3MBTL1 (0.50) | KDM4ERAB9ASMN1; SMN2L3MBTL1HTT | |
| SCHEMBL3883710 | 0.66 | KDM4E (0.41) | KDM4EL3MBTL1ALDH1A1MAPTGAA | |
| SCHEMBL1645505 | 0.64 | SMN1; SMN2 (0.39) | KDM4ERAB9ASMN1; SMN2L3MBTL1HTT | |
| SCHEMBL17397156 | 0.63 | KDM4E (0.35) | KDM4ERAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL31465684 | 0.61 | L3MBTL1 (0.47) | KDM4ERAB9AL3MBTL1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888063-B1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-01-14 | — | — | EP | claimed |