Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.66 |
| ▸ | CRHBP | P24387 | 1/20 | 0.66 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.66 |
| ▸ | CDC7 | O00311 | 9/20 | 0.54 |
| ▸ | DBF4 | Q9UBU7 | 9/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3739958 | 0.88 | MAPT (0.73) | MEN1KMT2AMAPTKDM4EHSP90AA1 | |
| SCHEMBL4478832 | 0.83 | CDC7 (0.75) | MEN1KMT2AMAPTKDM4EHSP90AA1 | |
| SCHEMBL4809770 | 0.82 | MAPT (0.70) | MEN1KMT2AMAPTKDM4EHSP90AA1 | |
| SCHEMBL2886858 | 0.81 | MAPT (0.80) | MEN1KMT2AMAPTKDM4EHSP90AA1 | |
| SCHEMBL4473140 | 0.80 | MAPT (0.61) | MEN1KMT2AMAPTKDM4EHSP90AA1 | |
| SCHEMBL4467427 | 0.80 | MAPT (0.67) | MEN1KMT2AMAPTKDM4EHSP90AA1 | |
| SCHEMBL8341363 | 0.80 | MAPT (0.78) | MEN1KMT2AMAPTKDM4EHSP90AA1 | |
| SCHEMBL4801129 | 0.80 | MAPT (0.78) | MEN1KMT2AMAPTKDM4EHSP90AA1 | |
| SCHEMBL4484447 | 0.79 | MAPT (0.76) | MEN1KMT2AMAPTKDM4EHSP90AA1 | |
| SCHEMBL4804421 | 0.79 | MAPT (0.76) | MEN1KMT2AMAPTKDM4EHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528160-B2 | Fused heterocyclic derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2009-05-05 | — | — | US | disclosed |