SCHEMBL446751

SCHEMBL446751

C#COCC[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14403348 0.72
SCHEMBL18849216 0.72
SCHEMBL1106 0.72
SCHEMBL27531737 0.71
SCHEMBL22716180 0.70
SCHEMBL14282515 0.69 TSHR (0.39)
SCHEMBL6847438 0.67
SCHEMBL1123426 0.67
SCHEMBL430949 0.65
SCHEMBL7081970 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3630738-B1 PROCESS FOR THE PRODUCTION OF OZANIMOD EGYT GYOGYSZERVEGYESZETI GYAR (HU) 2023-07-19 EP claimed
EP-2508504-B1 PROCESS FOR PREPARATION OF CYCLOALKANEDICARBOXYLIC ACID MONOESTERS SUMITOMO CHEMICAL CO (JP) 2016-04-13 EP claimed
EP-2727915-B1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof CONCERT PHARMACEUTICALS INC (US) 2016-04-13 EP claimed
JP-3099078-A None JP disclosed
EP-2419519-B1 PROCESS FOR PRODUCING (3R)-HYDROXYBUTYL (3R)-HYDROXYBUTYRATE BY ENZYMATIC ENANTIOSELECTIVE REDUCTION EMPLOYING ALCOHOL DEHYDROGENASES OR KETO REDUCTASES UNIV OXFORD INNOVATION LTD (GB) 2019-03-27 EP disclosed
EP-2343306-B1 Glycolipid derivatives, process for production of the same, intermediates for synthesis thereof, and process for production of the intermediates JAPAN PRESIDENT NAT CT NEUROLOGY & PSYCHIATRY (JP) 2018-04-04 EP disclosed
US-9034613-B2 Process for the preparation of (3R)-hydroxybutyl (3R)-hydroxybutyrate by enzymatic enantioselective reduction employing Lactobacillus brevis alcohol dehydrogenase ISIS INNOVATION LIMITED 2015-05-19 US disclosed
EP-2850088-A1 ACRYLIC ADHESION PROMOTERS COMPRISING PHOSPHONIC ACID AND ACRYLIC ACID ESTER!GROUPINGS Lord Corporation (US) 2015-03-25 EP disclosed
US-8859098-B2 Acrylic adhesion promoters LORD CORPORATION (US) 2014-10-14 US disclosed
EP-1619199-B1 GLYCOLIPID DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, INTERMEDIATES FOR SYNTHESIS THEREOF, AND PROCESS FOR PRODUCTION OF THE INTERMEDIATES JAPAN GOVERNMENT (JP) 2013-12-18 EP disclosed
US-20130309508-A1 ACRYLIC ADHESION PROMOTERS LORD CORPORATION 2013-11-21 US disclosed
WO-1995009159-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1995-04-06 WO disclosed
EP-0511879-B1 Pyrazine derivatives OTSUKA PHARMA CO LTD (JP) 1995-03-22 EP disclosed
WO-1995006630-A1 BENZYLAMINE DERIVATIVES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-03-09 WO disclosed
WO-1995006026-A1 DEHYDRATION OF ITACONIC ACID AKZO NOBEL N.V. (NL) 1995-03-02 WO disclosed
WO-1995002593-A1 PIPERAZINE DERIVATIVES AND SALTS THEREOF OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-01-26 WO disclosed
US-5238938-A Nephrosis OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-08-24 US disclosed
EP-0511879-A1 Pyrazine derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-11-04 EP disclosed
JP-H0399078-A PRODUCTION OF SUBSTANCE NF-1616-904 OTSUKA PHARMACEUT CO LTD 1991-04-24 JP disclosed
EP-0411150-A1 INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-02-06 EP disclosed