SCHEMBL44678

SCHEMBL44678

[CH2]C(C)C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isobutyraldehyde SCHEMBL17766468 0.73
SCHEMBL21708257 0.72
SCHEMBL6556809 0.70
Isobutyraldehyde SCHEMBL788159 0.70 ADH1B (0.38)
Isobutyraldehyde SCHEMBL2996 0.70
Isobutyraldehyde SCHEMBL2635854 0.70 ADH1B (0.38)
Isobutyraldehyde SCHEMBL18287436 0.70
SCHEMBL21708275 0.68
Ethylene SCHEMBL11406562 0.67
Isobutyraldehyde SCHEMBL2115232 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10597421-B2 Protected monomer and method of final deprotection for RNA synthesis AGILENT TECHNOLOGIES, INC. (US) 2020-03-24 US claimed
EP-2331558-B1 PROTECTED MONOMERS AND METHODS OF DEPROTECTION FOR RNA SYNTHESIS AGILENT TECHNOLOGIES INC (US) 2018-09-12 EP claimed
US-20180186826-A1 PROTECTED MONOMER AND METHOD OF FINAL DEPROTECTION FOR RNA SYNTHESIS AGILENT TECHNOLOGIES, INC. 2018-07-05 US claimed
US-9458258-B2 Process for the preparation of catalytic support and supported bimetallic catalysts for production of homopolymers and copolymers of ethylene with α-olefins, of high and ultra high molecular weight and with broad molecular weight distribution in slurry, bulk and gas phase processes and products thereof BRASKEM AMERICA, INC. (US) 2016-10-04 US claimed
EP-2050767-B1 Supported metallocene catalysts for production of polymers of ethylene with alpha- olefins, of high and ultra high molecular weight and with broad molecular weight distribution BRASKEM SA (BR) 2016-07-13 EP claimed
US-20160115106-A1 Stabilization of Chlorinated Olefins AXIALL OHIO, INC. 2016-04-28 US claimed
US-9273086-B2 Protected monomer and method of final deprotection for RNA synthesis AGILENT TECHNOLOGIES, INC. (US) 2016-03-01 US claimed
CN-105175433-A Spiro-oxindole compounds and their use as therapeutic agents XENON PHARMACEUTICALS INC 2015-12-23 CN claimed
CN-102947292-B nitrogen-containing heteroaryl compounds HOFFMAN-LA ROCHE LTD. (CH) 2015-08-19 CN claimed
CN-103664973-A Spiro-oxindole compounds and their use as therapeutic agents XENON PHARMACEUTICALS INC 2014-03-26 CN claimed
WO-2010026204-A1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD EVONIK RÖHM GMBH (DE) 2010-03-11 WO claimed
EP-2097415-A1 8-ETHINYLXANTHINE DERIVATIVES AS SELECTIVE A2A RECEPTOR ANTAGONISTS Schwarz Pharma AG (DE) 2009-09-09 EP claimed
CN-100526301-C 1, 2-di (cyclic) substituted benzene compounds EISAI R&D MAN CO LTD (JP) 2009-08-12 CN claimed
US-20090163682-A1 Process of Preparation of Catalytic Support and Supported Metallocene Catalysts for Production of Homopolymers and Copolymers of Ethylene with Alfa-Olefins, of High and Ultra High Molecular Weight and with Broad Molecular Weight Distribution in Slurry, Bulk and Gas Phase Processes and Products Thereof BRASKEM S/A (BR) 2009-06-25 US claimed
CN-101466727-A HCV/HIV inhibitors and uses thereof NOVARTIS AG (CH) 2009-06-24 CN claimed
EP-2050767-A1 Process for producing a catalytic support and supported metallocene catalysts for production of polymers of ethylene with alpha- olefins, of high and ultra high molecular weight and with broad molecular weight distribution and products resulting from said process Braskem S.A. (BR) 2009-04-22 EP claimed
WO-2008077557-A1 8-ETHINYLXANTHINE DERIVATIVES AS SELECTIVE A2A RECEPTOR ANTAGONISTS SCHWARZ PHARMA AG (DE) 2008-07-03 WO claimed
CN-101175723-A 1, 2-di (cyclic group) substituted benzene derivative EISAI R&D MAN CO LTD (JP) 2008-05-07 CN claimed
CN-1902170-A 1, 2-di (cyclic) substituted benzene compounds EISAI R&D MAN CO LTD (JP) 2007-01-24 CN claimed
US-4026956-A CONTAINING 1,3-DIOXOLANES OR 1,4-DIOXANE; ALIPHATIC ALDEHYDE HYDRAZONE PPG INDUSTRIES, INC. (US) 1977-05-31 US claimed