Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 2/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.34 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4489207 | 0.83 | CNR2 (0.58) | CNR2AGTR1AGTR2S1PR1KDM4E | |
| SCHEMBL4468766 | 0.77 | CNR2 (0.59) | CNR2S1PR1SLC2A1KDM4EUSP2 | |
| SCHEMBL1427580 | 0.75 | KDM4E (0.46) | KDM4EPIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL4478068 | 0.71 | CNR2 (0.65) | CNR2S1PR1SLC2A1KDM4EUSP2 | |
| SCHEMBL4697182 | 0.70 | CNR2 (0.78) | CNR2S1PR1 | |
| SCHEMBL9163392 | 0.70 | KDM4E (0.53) | AGTR1AGTR2KDM4EHTT | |
| SCHEMBL578799 | 0.70 | KDM4E (0.53) | AGTR1AGTR2KDM4EHTT | |
| SCHEMBL9390979 | 0.70 | KDM4E (0.53) | AGTR1AGTR2KDM4EHTT | |
| SCHEMBL578456 | 0.70 | KDM4E (0.53) | AGTR1AGTR2KDM4EHTT | |
| Hydrochloric Acid SCHEMBL38659118 | 0.69 | KDM4E (0.51) | AGTR1AGTR2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595397-B2 | Compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-29 | — | — | US | disclosed |