Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4475524 | 0.94 | CNR2 (0.87) | CNR2MEN1KMT2ABCHEACHE | |
| SCHEMBL4691061 | 0.94 | CNR2 (0.90) | CNR2MEN1KMT2ABCHEACHE | |
| SCHEMBL4476935 | 0.88 | CNR2 (1.00) | CNR2MEN1KMT2ASCD5S1PR1 | |
| SCHEMBL4476807 | 0.83 | MEN1 (0.63) | CNR2MEN1KMT2ABCHEACHE | |
| SCHEMBL4465139 | 0.79 | CNR2 (1.00) | CNR2 | |
| SCHEMBL4465145 | 0.79 | CNR2 (1.00) | CNR2 | |
| SCHEMBL4468766 | 0.78 | CNR2 (0.59) | CNR2S1PR1 | |
| SCHEMBL20148958 | 0.78 | ACHE (0.60) | MEN1KMT2ABCHEACHEBACE1 | |
| SCHEMBL4471675 | 0.78 | CNR2 (0.67) | CNR2MEN1KMT2ABCHEACHE | |
| SCHEMBL13708759 | 0.78 | CNR2 (0.70) | CNR2MEN1KMT2ASLC18A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966132-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |