SCHEMBL446802

SCHEMBL446802

CC(OC(=O)c1ccccc1N)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.56
HSD17B10 Q99714 11/20 0.56
CFTR P13569 1/20 0.56
KDM4E B2RXH2 7/20 0.54
TP53 P04637 2/20 0.51
HCAR2 Q8TDS4 1/20 0.49
HPGD P15428 5/20 0.46
TSHR P16473 3/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
GLA P06280 2/20 0.46
CYP3A4 P08684 1/20 0.46
MAPK1 P28482 1/20 0.46
HIF1A Q16665 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KMT2A Q03164 3/20 0.45
MEN1 O00255 1/20 0.45
NFKB1 P19838 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28087383 0.83 ALDH1A1 (0.51) ALDH1A1HSD17B10KDM4ETP53HCAR2
SCHEMBL21835626 0.83 ALDH1A1 (0.51) ALDH1A1HSD17B10KDM4ETP53HCAR2
SCHEMBL21835617 0.83 ALDH1A1 (0.51) ALDH1A1HSD17B10KDM4ETP53HCAR2
SCHEMBL8126578 0.83 ALDH1A1 (0.49) ALDH1A1HSD17B10CFTRKDM4ETP53
SCHEMBL2996221 0.83 ALDH1A1 (0.57) ALDH1A1HSD17B10KDM4ETP53HCAR2
SCHEMBL28171933 0.83 ALDH1A1 (0.41) ALDH1A1HSD17B10CFTRKDM4ETP53
SCHEMBL29979726 0.82 ALDH1A1 (0.63) ALDH1A1HSD17B10CFTRKDM4ETP53
SCHEMBL3507300 0.82 ALDH1A1 (0.63) ALDH1A1HSD17B10CFTRKDM4ETP53
SCHEMBL16672570 0.81 ALDH1A1 (0.52) ALDH1A1HSD17B10KDM4ETP53HCAR2
SCHEMBL16672838 0.81 ALDH1A1 (0.52) ALDH1A1HSD17B10KDM4ETP53HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4046491-B1 CONSUMER CARE PRODUCT FMC CORP (US) 2026-04-29 EP claimed
EP-4719062-A2 METHODS FOR IMPROVING PLANT RESPONSE TO PESTS AND PATHOGENS Newleaf Symbiotics, Inc. (US) 2026-04-08 EP claimed
WO-2024243521-A2 METHODS FOR IMPROVING PLANT RESPONSE TO PESTS AND PATHOGENS NEWLEAF SYMBIOTICS, INC. (US) 2024-11-28 WO claimed
EP-4046491-A1 INSECT REPELLENT FMC Corporation (US) 2022-08-24 EP claimed
US-20200163334-A1 INSECT REPELLENT LINTZ, DONNA 2020-05-28 US claimed
US-10178865-B2 Insect repellent FMC CORPORATION (US) 2019-01-15 US claimed
EP-3422853-A1 INSECT REPELLENT FMC Corporation (US) 2019-01-09 EP claimed
CN-109068644-A Insect repellant FMC有限公司 2018-12-21 CN claimed
WO-2018145219-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ADDICTIONS BY MEANS OF AVERSIVE COUNTERCONDITIONING SERANI MOSTAZAL JORGE (CL) 2018-08-16 WO claimed
US-9930886-B2 Nematode repellent composition FMC CORPORATION (US) 2018-04-03 US claimed
CN-105377034-A Nematode repellent composition FMC CORP 2016-03-02 CN claimed
US-20150025141-A1 Insect Repellent FMC CORPORATION 2015-01-22 US claimed
WO-2015009905-A1 NEMATODE REPELLENT COMPOSITION FMC CORPORATION (US) 2015-01-22 WO claimed
WO-2015009911-A1 INSECT REPELLENT FMC CORPORATION (US) 2015-01-22 WO claimed
US-20150025140-A1 NEMATODE REPELLENT COMPOSITION FMC CORPORATION 2015-01-22 US claimed
US-6369248-B1 HYDROXY ESTERS FOR PERFUMES GIVAUDAN SA (CH) 2002-04-09 US claimed
EP-1004654-A2 Adjuvants and methods for raising intracellular calcium ion concentration Takasago International Corporation (JP) 2000-05-31 EP claimed
EP-0989970-A1 FRAGRANCE PRECURSOR COMPOUNDS GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 2000-04-05 EP claimed
EP-0980863-A1 Oxime carboxylic acid derivatives Givaudan Roure (International) S.A. (CH) 2000-02-23 EP claimed
WO-1998058899-A1 FRAGRANCE PRECURSOR COMPOUNDS GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1998-12-30 WO claimed