Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL654064 | 0.92 | DRD2 (0.41) | DRD2OPRM1OPRL1CCR1ADRA1A | |
| SCHEMBL654062 | 0.92 | DRD2 (0.41) | DRD2OPRM1OPRL1CCR1ADRA1A | |
| SCHEMBL654383 | 0.90 | DRD2 (0.43) | DRD2OPRM1CCR1ADRA1A | |
| SCHEMBL654381 | 0.90 | DRD2 (0.43) | DRD2OPRM1CCR1ADRA1A | |
| SCHEMBL654870 | 0.90 | DRD2 (0.41) | DRD2CCR1ADRA1A | |
| SCHEMBL654872 | 0.90 | DRD2 (0.41) | DRD2CCR1ADRA1A | |
| SCHEMBL655038 | 0.89 | DRD2 (0.44) | DRD2OPRM1OPRL1CCR1ADRA1A | |
| SCHEMBL655036 | 0.89 | DRD2 (0.44) | DRD2OPRM1OPRL1CCR1ADRA1A | |
| SCHEMBL655208 | 0.89 | DRD2 (0.44) | DRD2ADRA1A | |
| SCHEMBL655210 | 0.89 | DRD2 (0.44) | DRD2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541365-B2 | Chemokine receptor antagonists and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-06-02 | — | — | US | disclosed |