⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1229957 | 0.77 | HSD17B10 (0.48) | — | |
| SCHEMBL9538524 | 0.76 | GRM5 (0.40) | — | |
| SCHEMBL8625648 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL29951446 | 0.74 | HSD17B10 (0.33) | — | |
| SCHEMBL2492972 | 0.74 | — | — | |
| SCHEMBL25401363 | 0.72 | — | — | |
| SCHEMBL7944939 | 0.72 | — | — | |
| SCHEMBL18131703 | 0.72 | — | — | |
| SCHEMBL22888399 | 0.72 | — | — | |
| SCHEMBL21993012 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 436 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073382-A | Preparation method of 2-chloro-pyrimidine-5-formaldehyde | 乐威医药（江苏）股份有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-109928933-B | 2-chloro-5-aldehyde pyrimidine and preparation method thereof | 安徽昊帆生物有限公司 | 2021-02-26 | — | — | CN | claimed |
| CN-107383014-B | A kind of 1H- pyrazolo [3,4-d] pyrimidines and its preparation method and application | 南方医科大学 | 2019-04-30 | — | — | CN | claimed |
| CN-106496232-B | A kind of 1- with anti-tumor activity (2- oxinanes) -1H- pyrazolos [3,4-d] pyrimidines and preparation method thereof | 南方医科大学 | 2018-11-09 | — | — | CN | claimed |
| CN-108467368-A | A kind of preparation method of bis- chloro- 5- pyrimidinecarboxaldehydes of medicine intermediate 2,4- | 郑州盖科科技有限公司 | 2018-08-31 | — | — | CN | claimed |
| CN-107383014-A | A kind of 1H pyrazolos [3,4 d] pyrimidines and its preparation method and application | 南方医科大学 | 2017-11-24 | — | — | CN | claimed |
| CN-106496232-A | A kind of 1 (2 oxinane) 1H pyrazolos [3,4 d] pyrimidines with antitumor activity and preparation method thereof | 南方医科大学 | 2017-03-15 | — | — | CN | claimed |
| CN-104844573-A | Miazines BTK inhibitor, preparation method and medical application thereof | UNIV CHINA PHARMA | 2015-08-19 | — | — | CN | claimed |
| EP-4746911-A1 | PHOSPHORAMIDITE LINKERS | United Kingdom Research and Innovation (GB) | 2026-05-27 | — | — | EP | disclosed |
| EP-4747248-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | Institute of Cancer Research: Royal Cancer Hospital (The) (GB) | 2026-05-27 | — | — | EP | disclosed |
| CN-122071464-A | Heterocyclic compound, pharmaceutical composition thereof and application thereof | 上海璎黎药业有限公司 | 2026-05-22 | — | — | CN | disclosed |
| WO-2026099466-A1 | TARGETED PROTEIN DEGRADATION | MONTE ROSA THERAPEUTICS AG (CH) | 2026-05-15 | — | — | WO | disclosed |
| US-12624024-B2 | EP2 antagonist compounds | RESERVOIR NEUROSCIENCE, INC. (US) | 2026-05-12 | — | — | US | disclosed |
| US-12622917-B2 | High-activity Wnt pathway inhibitor compound | ADLAI NORTYE BIOPHARMA CO., LTD. (CN) | 2026-05-12 | — | — | US | disclosed |
| US-5298507-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-03-29 | — | — | US | disclosed |
| US-5204360-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5001138-A | Insecticides | NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) | 1991-03-19 | — | — | US | disclosed |
| US-4845106-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4742060-A | 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |