Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.77 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.77 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.77 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | MGAM | O43451 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SI | P14410 | 1/20 | 0.57 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13783895 | 0.87 | CSNK2A2 (0.75) | CSNK2A2CSNK2A1CSNK2BHDAC1HDAC2 | |
| SCHEMBL10750591 | 0.83 | CSNK2A2 (0.69) | CSNK2A2CSNK2A1CSNK2BHDAC1HDAC2 | |
| SCHEMBL3828303 | 0.79 | NPC1 (0.71) | CSNK2A2CSNK2A1MEN1KMT2ARAB9A | |
| SCHEMBL1594204 | 0.79 | CSNK2A2 (0.50) | CSNK2A2CSNK2A1CSNK2BHDAC1HDAC2 | |
| SCHEMBL1594202 | 0.79 | CSNK2A2 (0.50) | CSNK2A2CSNK2A1CSNK2BHDAC1HDAC2 | |
| SCHEMBL4459490 | 0.78 | HDAC1 (0.62) | CSNK2A2CSNK2A1HDAC1HDAC2MAPT | |
| SCHEMBL28007100 | 0.78 | CSNK2A2 (0.55) | CSNK2A2CSNK2A1CSNK2BHDAC1HDAC2 | |
| SCHEMBL11395495 | 0.77 | CSNK2A2 (0.65) | CSNK2A2CSNK2A1CSNK2BHDAC1HDAC2 | |
| SCHEMBL13723187 | 0.76 | GAA (0.66) | CSNK2A2CSNK2A1CSNK2BHDAC1HDAC2 | |
| SCHEMBL8880665 | 0.75 | MGAM (0.56) | CSNK2A2CSNK2A1CSNK2BHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |