Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | HPN | P05981 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20522351 | 0.85 | CSNK2A2 (0.70) | HDAC1HDAC2BLMHPNCA1 | |
| SCHEMBL3828303 | 0.84 | NPC1 (0.71) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL7930408 | 0.81 | HDAC1 (0.67) | HDAC1HDAC2BLMHPNCA1 | |
| SCHEMBL11386451 | 0.80 | ALDH1A1 (0.58) | HDAC1HDAC2BLMHPNCSNK2A2 | |
| SCHEMBL4468253 | 0.78 | CSNK2A2 (0.77) | HDAC1HDAC2BLMCSNK2A2CSNK2A1 | |
| SCHEMBL20522295 | 0.78 | CSNK2A2 (0.60) | HDAC1HDAC2BLMHPNCA1 | |
| SCHEMBL12986710 | 0.77 | HDAC1 (0.77) | HDAC1HDAC2HPNHDAC3HDAC4 | |
| SCHEMBL11392290 | 0.77 | RXFP1 (0.65) | HDAC1HDAC2BLMHPNCSNK2A2 | |
| SCHEMBL18762150 | 0.76 | BLM (0.70) | HDAC1HDAC2BLMCSNK2A2CSNK2A1 | |
| SCHEMBL22532425 | 0.76 | CSNK2A2 (0.62) | HDAC1HDAC2CSNK2A2CSNK2A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |