Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 17/20 | 0.72 |
| ▸ | CA1 | P00915 | 16/20 | 0.72 |
| ▸ | CA2 | P00918 | 16/20 | 0.72 |
| ▸ | CA12 | O43570 | 8/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.72 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13970758 | 0.86 | CA9 (0.83) | CA9CA1CA2CA12CA14 | |
| SCHEMBL19818217 | 0.84 | CA9 (0.77) | CA9CA1CA2CA12CA14 | |
| SCHEMBL13070942 | 0.84 | CA9 (1.00) | CA9CA1CA2CA12CA14 | |
| SCHEMBL24444501 | 0.83 | CA9 (0.72) | CA9CA1CA2CA12CA14 | |
| SCHEMBL2234764 | 0.82 | CA9 (0.83) | CA9CA1CA2CA12CA14 | |
| SCHEMBL15828111 | 0.82 | CA9 (0.83) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14164948 | 0.81 | CA9 (0.72) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12678101 | 0.81 | CA9 (0.72) | CA9CA1CA2CA12CA14 | |
| SCHEMBL2742845 | 0.81 | CA9 (0.58) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14642801 | 0.81 | CA1 (0.67) | CA9CA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156825-A1 | Fluorescent compounds that bind to histone deacetylase | MERCK SHARP & DOHME CORP. | 2009-06-18 | — | — | US | claimed |
| US-20090156825-A1 | Fluorescent compounds that bind to histone deacetylase | MERCK SHARP & DOHME CORP. | 2009-06-18 | — | — | US | disclosed |
| US-20090156825-A1 | Fluorescent compounds that bind to histone deacetylase | MERCK SHARP & DOHME CORP. | 2009-06-18 | — | — | US | disclosed |
| US-20090156825-A1 | Fluorescent compounds that bind to histone deacetylase | MERCK SHARP & DOHME CORP. | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156825-A1 | Fluorescent compounds that bind to histone deacetylase | HDAC1, HDAC3, HDAC11 | CA9 3944/4885CA1 2751/4885CA2 2969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.