Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 15/20 | 0.58 |
| ▸ | CA1 | P00915 | 14/20 | 0.58 |
| ▸ | CA2 | P00918 | 14/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 6/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17067944 | 0.86 | CA9 (0.61) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL14527509 | 0.83 | CA9 (0.66) | CA9CA1CA2USP2L3MBTL1 | |
| 5-Iodoacetamidofluorescein SCHEMBL10146553 | 0.83 | CA9 (0.66) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL12793932 | 0.83 | CA9 (0.66) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL14426895 | 0.83 | USP2 (0.68) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL16421785 | 0.83 | CA9 (0.61) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL18559017 | 0.83 | CA9 (0.60) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL14806740 | 0.82 | CA9 (0.60) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL20059101 | 0.82 | CA9 (0.64) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL15150500 | 0.82 | CA9 (0.59) | CA9CA1CA2USP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2793027-B1 | Unnatural reactive amino acid genetic code additions | SCRIPPS RESEARCH INST (US) | 2019-11-13 | — | — | EP | disclosed |
| US-9797908-B2 | Unnatural reactive amino acid genetic code additions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-10-24 | — | — | US | disclosed |
| US-9797908-B2 | Unnatural reactive amino acid genetic code additions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-10-24 | — | — | US | disclosed |
| US-9580721-B2 | Expanding the eukaryotic genetic code | The Scripps Reserach Institute (US) | 2017-02-28 | — | — | US | disclosed |
| US-9580721-B2 | Expanding the eukaryotic genetic code | The Scripps Reserach Institute (US) | 2017-02-28 | — | — | US | disclosed |
| EP-2410331-B1 | Aminoacyl-tRNA synthetase for aminoacylation tRNA with unnatural amino acids | SCRIPPS RESEARCH INST (US) | 2015-09-23 | — | — | EP | disclosed |
| US-20150240249-A1 | EXPANDING THE EUKARYOTIC GENETIC CODE | SCRIPPS RESEARCH INST (US) | 2015-08-27 | — | — | US | disclosed |
| US-20150240249-A1 | EXPANDING THE EUKARYOTIC GENETIC CODE | SCRIPPS RESEARCH INST (US) | 2015-08-27 | — | — | US | disclosed |
| US-8945926-B2 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-02-03 | — | — | US | disclosed |
| US-8945926-B2 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-02-03 | — | — | US | disclosed |
| US-7608423-B2 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-10-27 | — | — | US | disclosed |
| US-20090137424-A1 | Selective Posttranslational Modification of Phage-Displayed Polypeptides | THE SCRIPPS RESEARCH INSTITUTE | 2009-05-28 | — | — | US | disclosed |
| US-20080227195-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-09-18 | — | — | US | disclosed |
| US-20080227195-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-09-18 | — | — | US | disclosed |
| US-20080176277-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-07-24 | — | — | US | disclosed |
| US-20080176277-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-07-24 | — | — | US | disclosed |
| US-20070166791-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-19 | — | — | US | disclosed |
| US-20070166791-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-19 | — | — | US | disclosed |
| US-20070154952-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-05 | — | — | US | disclosed |
| US-20070154952-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070154952-A1 | Expanding the eukaryotic genetic code | NSUN3, AARS1, TRMT1 | CA9 4064/4885CA1 4466/4885CA2 3832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.