SCHEMBL446877

SCHEMBL446877

CC(C)=COC(=O)CCC(=O)OC=C(C)C

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 3/20 0.33
ADRA2A P08913 1/20 0.32
ADRA1A P35348 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
KDM6B O15054 1/20 0.31
KDM5C P41229 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31
ALOX15 P16050 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL848574 0.91 PHF8 (0.45) TSHRALDH1A1KDM6BKDM5CEGLN1
SCHEMBL28047872 0.91 TSHR (0.59) TSHRALDH1A1MGAMGAASI
SCHEMBL28049493 0.89 TSHR (0.33) TSHR
SCHEMBL28746797 0.89 TSHR (0.33) TSHR
SCHEMBL5690184 0.89 TSHR (0.33) TSHRMGAMGAASIMGAM2
SCHEMBL28503090 0.89 PHF8 (0.43) TSHRALDH1A1KDM6BKDM5CEGLN1
SCHEMBL28296514 0.87 ALDH1A1 (0.50) TSHRALDH1A1MAPTLMNA
SCHEMBL28236422 0.87 SQLE (0.31) TSHR
SCHEMBL8951891 0.87 FFAR3 (0.39) TSHR
SCHEMBL27574835 0.87 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1677 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12234609-B2 Method for manufacturing paper and cardboard SNF GROUP (FR) 2025-02-25 US claimed
US-20240384159-A1 DISPERSION OF WATER-SOLUBLE POLYMER FOR HYDRAULIC FRACTURING SNF GROUP (FR) 2024-11-21 US claimed
CN-116355676-B Composite antioxidant for prolonging induction period of lubricating oil and preparation method thereof 江西亮华科技有限公司 2024-10-01 CN claimed
WO-2024149635-A1 BRANCHED AMINES AS ADDITIVES FOR GASOLINE FUELS BASF SE (DE) 2024-07-18 WO claimed
US-12031099-B2 Marine fuels INFINEUM INTERNATIONAL LIMITED (GB) 2024-07-09 US claimed
CN-118119688-A Reduction of asphaltenes from marine fuels 巴斯夫欧洲公司 2024-05-31 CN claimed
CN-118119689-A Reduction of asphaltenes from marine fuels 巴斯夫欧洲公司 2024-05-31 CN claimed
CN-116096963-B Method for producing paper and board 爱森集团 2024-05-17 CN claimed
CN-118043430-A Dispersion of water-soluble polymers for hydraulic fracturing 爱森集团 2024-05-14 CN claimed
CN-112300842-B Demulsifier for fuel containing quaternary ammonium salt 雅富顿化学公司 2024-04-05 CN claimed
EP-0212922-A2 Overbased Additives EXXON CHEMICAL PATENTS INC. (US) 1987-03-04 EP claimed
US-4428849-A ACID-TREATED JPOLYISOBUTENYL SUCCINIMIDES EXXON RESEARCH & ENGINEERING CO. (US) 1984-01-31 US claimed
US-4404301-A Polymeric light stabilizers having at least one 2,2,6,6-tetraalkyl piperidyl group and synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-09-13 US claimed
US-4394277-A Method for improving fuel economy of internal combustion engines using borated sulfur-containing 1,2-alkane diols CHEVRON RESEARCH COMPANY (US) 1983-07-19 US claimed
US-4394276-A Method for improving fuel economy of internal combustion engines using sulfur-containing alkanediols CHEVRON RESEARCH COMPANY (US) 1983-07-19 US claimed
EP-0065655-A1 Polymeric light stabilizers having at least one 2,2,6,6-tetraalkyl piperidyl group and synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1982-12-01 EP claimed
US-4276388-A UNSATURATED POLYESTER, DIALKYL ESTER OF ALKENYL SUCCINIC ACID AND AN UNSATURATED COMPOUND HITACHI CHEMICAL COMPANY, LTD. (JP) 1981-06-30 US claimed
US-4174322-A Thiobis(oxazolines) EXXON RESEARCH & ENGINEERING CO. (US) 1979-11-13 US claimed
US-4119553-A POLYISOBUTENYL SUCCINIC ANHYDRIDE ESTERIFICATION WITH POLYHYDRIC ALCOHOL BP CHEMICALS LIMITED (GB) 1978-10-10 US claimed
US-3998772-A EMULSIFYING AN ELASTOMER CEMENT WITH WATER, A SOAP OF A FATTY ACID AND A STABILIZER ADDITIVE BEERBOWER ALAN 1976-12-21 US claimed