Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 3/20 | 0.32 |
| ▸ | CES1 | P23141 | 3/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1698256 | 1.00 | — | — | |
| SCHEMBL10886026 | 1.00 | TSHR (0.38) | TSHRLMNANFKB1PMP22FAAH | |
| SCHEMBL27858750 | 1.00 | TSHR (0.38) | TSHRLMNANFKB1PMP22FAAH | |
| SCHEMBL28379533 | 0.97 | LMNA (0.36) | TSHRLMNANFKB1PMP22FAAH | |
| SCHEMBL28379521 | 0.97 | LMNA (0.36) | TSHRLMNANFKB1PMP22FAAH | |
| SCHEMBL7352594 | 0.97 | — | — | |
| SCHEMBL28379523 | 0.94 | — | — | |
| SCHEMBL2763314 | 0.88 | — | — | |
| SCHEMBL16429437 | 0.87 | TSHR (0.47) | TSHRLMNANFKB1PMP22HDAC3 | |
| SCHEMBL689239 | 0.87 | TSHR (0.47) | TSHRLMNANFKB1PMP22HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423749-B1 | LIQUID CRYSTAL SWITCHING MECHANISM | WISCONSIN ALUMNI RES FOUND (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-1423749-A4 | LIQUID CRYSTAL SWITCHING MECHANISM | WISCONSIN ALUMNI RES FOUND (US) | 2005-12-21 | — | — | EP | disclosed |
| US-6824837-B2 | Liquid crystal switching mechanism | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2004-11-30 | — | — | US | disclosed |
| EP-1423749-A2 | LIQUID CRYSTAL SWITCHING MECHANISM | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2004-06-02 | — | — | EP | disclosed |
| US-20030071949-A1 | Liquid crystal switching mechanism | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-04-17 | — | — | US | disclosed |
| WO-2003021339-A2 | LIQUID CRYSTAL SWITCHING MECHANISM | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2003-03-13 | — | — | WO | disclosed |