Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.70 |
| ▸ | ACHE | P22303 | 1/20 | 0.70 |
| ▸ | TYR | P14679 | 3/20 | 0.66 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Licoricidin SCHEMBL744305 | 0.84 | PTPN1 (1.00) | PTPN1ACHETYR | |
| Licoricidin SCHEMBL30631340 | 0.84 | PTPN1 (1.00) | PTPN1ACHETYR | |
| Licoricidin SCHEMBL22704769 | 0.84 | PTPN1 (1.00) | PTPN1ACHETYR | |
| Licoricidin SCHEMBL30405793 | 0.84 | PTPN1 (1.00) | PTPN1ACHETYR | |
| Glycycoumarin SCHEMBL759406 | 0.81 | PTPN1 (0.75) | PTPN1ACHETYRDYRK1ACYP19A1 | |
| Glycycoumarin SCHEMBL29390258 | 0.81 | PTPN1 (0.75) | PTPN1ACHETYRDYRK1ACYP19A1 | |
| Glyasperin C SCHEMBL25168190 | 0.81 | TYR (1.00) | PTPN1ACHETYRDYRK1A | |
| Glyasperin C SCHEMBL29390338 | 0.81 | TYR (1.00) | PTPN1ACHETYRDYRK1A | |
| Glyasperin C SCHEMBL14701584 | 0.81 | TYR (1.00) | PTPN1ACHETYRDYRK1A | |
| SCHEMBL8093438 | 0.81 | PTPN1 (0.89) | PTPN1ACHETYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578401-A4 | COMPOSITIONS AND METHODS FOR PROMOTING WEIGHT LOSS, THERMOGENESIS, APPETITE SUPPRESSION, LEAN MUSCLE MASS, INCREASING METABOLISM AND BOOSTING ENERGY LEVELS, AND USE AS A DIETARY SUPPLEMENT IN MAMMALS | RTC RES & DEV LLC (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1578401-A2 | COMPOSITIONS AND METHODS FOR PROMOTING WEIGHT LOSS, THERMOGENESIS, APPETITE SUPPRESSION, LEAN MUSCLE MASS, INCREASING METABOLISM AND BOOSTING ENERGY LEVELS, AND USE AS A DIETARY SUPPLEMENT IN MAMMALS | RTC Research & Development, LLC. (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20040077556-A1 | Compositions and methods for promoting weight loss, thermogenesis, appetite suppression, lean muscle mass, increasing metabolism and boosting energy levels, and use as a dietary supplement in mammals | RTC RESEARCH AND DEVELOPMENT, LLC | 2004-04-22 | — | — | US | disclosed |
| WO-2003090673-A2 | COMPOSITIONS AND METHODS FOR PROMOTING WEIGHT LOSS, THERMOGENESIS, APPETITE SUPPRESSION, LEAN MUSCLE MASS, INCREASING METABOLISM AND BOOSTING ENERGY LEVELS, AND USE AS A DIETARY SUPPLEMENT IN MAMMALS | RTC RESEARCH & DEVELOPMENT, LLC. (US) | 2003-11-06 | — | — | WO | disclosed |