Glycycoumarin

Glycycoumarin

SCHEMBL759406

COc1c(CC=C(C)C)c(O)cc2oc(=O)c(-c3ccc(O)cc3O)cc12

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 9/20 0.75
▸ DYRK1A Q13627 1/20 0.75
▸ PDE4D Q08499 4/20 0.54
▸ AKT1 P31749 1/20 0.52
▸ ACHE P22303 2/20 0.51
▸ TUBB4A P04350 1/20 0.49
▸ TUBB P07437 1/20 0.49
▸ TUBA3C P0DPH7 1/20 0.49
▸ TUBA1B P68363 1/20 0.49
▸ TUBA4A P68366 1/20 0.49
▸ TUBB4B P68371 1/20 0.49
▸ TUBB3 Q13509 1/20 0.49
▸ TUBB2A Q13885 1/20 0.49
▸ TUBB8 Q3ZCM7 1/20 0.49
▸ TUBA3E Q6PEY2 1/20 0.49
▸ TUBA1A Q71U36 1/20 0.49
▸ TUBA1C Q9BQE3 1/20 0.49
▸ TUBB6 Q9BUF5 1/20 0.49
▸ TUBB2B Q9BVA1 1/20 0.49
▸ TUBB1 Q9H4B7 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycycoumarin SCHEMBL29390258 1.00 PTPN1 (0.75) PTPN1DYRK1APDE4DAKT1ACHE
Glycyrin SCHEMBL5327472 0.94 PTPN1 (0.75) PTPN1DYRK1APDE4DAKT1ACHE
Glycyrin SCHEMBL29388094 0.94 PTPN1 (0.75) PTPN1DYRK1APDE4DAKT1ACHE
Licocoumarone SCHEMBL30220504 0.86 PTPN1 (1.00) PTPN1DYRK1APDE4DAKT1TUBB4A
Licocoumarone SCHEMBL758659 0.86 PTPN1 (1.00) PTPN1DYRK1APDE4DAKT1TUBB4A
Licoricidin SCHEMBL4468990 0.81 PTPN1 (0.70) PTPN1DYRK1APDE4DAKT1ACHE
SCHEMBL29391195 0.79 PTPN1 (1.00) PTPN1DYRK1APDE4DAKT1ACHE
SCHEMBL22704765 0.79 PTPN1 (1.00) PTPN1DYRK1APDE4DAKT1ACHE
Glycyrol SCHEMBL758197 0.78 ALOX5AP (0.65) PTPN1DYRK1APDE4DAKT1TUBB4A
Glycyrol SCHEMBL29499208 0.78 ALOX5AP (0.65) PTPN1DYRK1APDE4DAKT1TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250177467-A1 COMPOSITIONS AND METHODS FOR MODULATING NUCLEAR FACTOR OF ACTIVATED T-CELLS (NFAT) ACTIVITY OF T CELLS UNIV YALE (US) 2025-06-05 — — US claimed
EP-4486363-A1 COMPOSITIONS AND METHODS FOR MODULATING NUCLEAR FACTOR OF ACTIVATED T-CELLS (NFAT) ACTIVITY OF T CELLS Yale University (US) 2025-01-08 — — EP claimed
WO-2024033113-A1 ACTIVE AGENT MODULATING THE ACTIVITY OF AN ION CHANNEL FOR USE IN REGULATION OF SKIN PIGMENTATION CUTANEON - SKIN & HAIR INNOVATIONS GMBH (DE) 2024-02-15 — — WO claimed
EP-4321148-A1 ACTIVE AGENT MODULATING THE ACTIVITY OF AN ION CHANNEL FOR USE IN REGULATION OF SKIN PIGMENTATION CUTANEON - Skin & Hair Innovations GmbH (DE) 2024-02-14 — — EP claimed
WO-2023167869-A1 COMPOSITIONS AND METHODS FOR MODULATING NUCLEAR FACTOR OF ACTIVATED T-CELLS (NFAT) ACTIVITY OF T CELLS YALE UNIVERSITY (US) 2023-09-07 — — WO claimed
US-20230276831-A1 Food/Beverage Article KIKKOMAN CORPORATION (JP) 2023-09-07 — — US claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 — — CN claimed
EP-4176731-A1 FOOD/BEVERAGE ARTICLE Kikkoman Corporation (JP) 2023-05-10 — — EP claimed
CN-115901978-A Detection method of traditional Chinese medicine composition 山东新时代药业有限公司 2023-04-04 — — CN claimed
CN-111443154-B Research method of medicinal genetic relationship of glycyrrhiza 贵州中医药大学 2023-03-07 — — CN claimed
CN-105497018-A Novel application of glycycoumarin as PBK/TOPK (PDZbinding-kinase/T-LAK celloriginated protein kinase) protein inhibitor UNIV CHINA AGRICULTURAL 2016-04-20 — — CN claimed
CN-103565800-B Novel application of glycycoumarin in prevention and treatment of alcoholic liver injury UNIV CHINA AGRICULTURAL 2015-06-17 — — CN claimed
CN-103565800-A Novel application of glycycoumarin in prevention and treatment of alcoholic liver injury UNIV CHINA AGRICULTURAL 2014-02-12 — — CN claimed
US-7888388-B2 Peroxisome proliferator activated receptor ligand and process for producing the same KANEKA CORPORATION (JP) 2011-02-15 — — US claimed
US-20090036519-A1 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR LIGAND AND PROCESS FOR PRODUCING THE SAME KANEKA CORPORATION (JP) 2009-02-05 — — US claimed
CN-1633302-A Method for producing high-quality hydrophobic licorice extract KANEGAFUCHI CHEMICAL IND (JP) 2005-06-29 — — CN claimed
US-20050118288-A1 Method for producing high-quality hydropbic licorice extract KANEKA CORPORATION (JP) 2005-06-02 — — US claimed
US-20050014819-A1 Peroxisome proliferator activated receptor ligands and process for producing the same KANEKA CORPORATION (JP) 2005-01-20 — — US claimed
EP-1477177-A1 PROCESS FOR PRODUCING HYDROPHOBIC GLYCYRRHIZA EXTRACT WITH HIGH QUALITIES KANEKA CORPORATION (JP) 2004-11-17 — — EP claimed
EP-1440688-A1 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR LIGANDS AND PROCESS FOR PRODUCING THE SAME KANEKA CORPORATION (JP) 2004-07-28 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036519-A1 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR LIGAND AND PROCESS FOR PRODUCING THE SAME PPARG, PPARA, PPARD PTPN1 945/4885DYRK1A 3340/4885PDE4D 4132/4885
US-20050014819-A1 Peroxisome proliferator activated receptor ligands and process for producing the same PPARG, PPARA, PPARD PTPN1 933/4885DYRK1A 3269/4885PDE4D 3902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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