SCHEMBL4469294

SCHEMBL4469294

CCCCCCCCc1cc(O)ccc1C(C)(C)c1cccc(C(C)(C)c2ccc(O)cc2CCCCCCCC)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.51
CYP3A4 P08684 3/20 0.51
TYR P14679 2/20 0.51
TP53 P04637 2/20 0.51
MAPT P10636 2/20 0.51
MEN1 O00255 1/20 0.51
ALOX15 P16050 1/20 0.51
TSHR P16473 1/20 0.51
HTT P42858 1/20 0.51
KMT2A Q03164 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
ESR1 P03372 3/20 0.45
ESR2 Q92731 1/20 0.45
PTGS2 P35354 4/20 0.41
ADRA2A P08913 2/20 0.41
ADORA3 P0DMS8 2/20 0.41
TACR2 P21452 2/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4472437 1.00 ALOX5 (0.51) ALOX5CYP3A4TYRTP53MAPT
SCHEMBL4469282 0.99 ALOX5 (0.49) ALOX5CYP3A4TYRTP53MAPT
SCHEMBL4457051 0.94 TYR (0.49) ALOX5CYP3A4TYRTP53MAPT
SCHEMBL4474773 0.88 ESR1 (0.50) ALOX5CYP3A4TYRTP53MAPT
SCHEMBL4465516 0.82 ESR1 (0.53) CYP3A4TYRALOX15TSHRHTT
SCHEMBL8582208 0.82 TYR (0.58) ALOX5CYP3A4TYRTP53MAPT
SCHEMBL4470339 0.79 ESR1 (0.46) CYP3A4TYRALOX15HTTESR1
SCHEMBL4457785 0.77 ESR1 (0.50) CYP3A4TYRALOX15TSHRHTT
SCHEMBL29003638 0.76 TYR (0.58) ALOX5CYP3A4TYRTP53MAPT
SCHEMBL11213586 0.75 TYR (0.43) ALOX5CYP3A4TYRTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed