Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.37 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137985 | 0.86 | TDP1 (0.44) | TDP1VCAM1TSHRMAPK1ATM | |
| SCHEMBL285845 | 0.81 | VCAM1 (0.46) | TDP1VCAM1TSHRMAPK1ATM | |
| SCHEMBL1115822 | 0.81 | TDP1 (0.62) | TDP1VCAM1TSHRMAPK1ALDH1A1 | |
| SCHEMBL2551163 | 0.79 | TDP1 (0.63) | TDP1VCAM1TSHRMAPK1ATM | |
| SCHEMBL29940081 | 0.79 | TDP1 (0.63) | TDP1VCAM1TSHRMAPK1ATM | |
| SCHEMBL25339295 | 0.79 | VCAM1 (0.43) | TDP1VCAM1TSHRMAPK1ATM | |
| SCHEMBL15776847 | 0.79 | TDP1 (0.47) | TDP1VCAM1TSHRMAPK1ATM | |
| SCHEMBL9098746 | 0.78 | VCAM1 (0.46) | TDP1VCAM1TSHRMAPK1ATM | |
| SCHEMBL31342321 | 0.77 | TDP1 (0.55) | TDP1VCAM1TSHRMAPK1ATM | |
| SCHEMBL3723529 | 0.77 | TDP1 (0.55) | TDP1VCAM1TSHRMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164775-A | Polycyclic compounds and methods for rapid accelerated targeted degradation of fibrosarcoma polypeptides | 阿尔维纳斯运营股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-1836202-B1 | AMINOPHENYL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | ACADIA PHARM INC (US) | 2016-12-21 | — | — | EP | disclosed |
| US-20090270449-A1 | AMINOPHENYL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SCHLIENGER NATHALIE | 2009-10-29 | — | — | US | disclosed |
| US-7585877-B2 | Aminophenyl derivatives as selective androgen receptor modulators | ACADIA PHARMACEUTICALS, INC. | 2009-09-08 | — | — | US | disclosed |
| CN-101119993-A | Aminophenyl derivatives as selective androgen receptor modulators | ACADIA PHARM INC (US) | 2008-02-06 | — | — | CN | disclosed |
| WO-2006076317-A9 | AMINOPHENYL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | ACADIA PHARM INC (US) | 2007-09-27 | — | — | WO | disclosed |
| EP-1836202-A2 | AMINOPHENYL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | Acadia Pharmaceuticals Inc. (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2007092400-A1 | AMINOPHENYL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | ACADIA PHARMACEUTICALS INC. (US) | 2007-08-16 | — | — | WO | disclosed |
| US-20060173037-A1 | Aminophenyl derivatives as selective androgen receptor modulators | ACADIA PHARMACEUTICALS INC. | 2006-08-03 | — | — | US | disclosed |
| WO-2006076317-A2 | AMINOPHENYL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | ACADIA PHARMACEUTICALS INC. (US) | 2006-07-20 | — | — | WO | disclosed |
| US-20060160845-A1 | Aminophenyl derivatives as selective androgen receptor modulators | ACADIA PHARMACEUTICALS INC. | 2006-07-20 | — | — | US | disclosed |
| EP-0174131-A2 | Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them | FISONS plc (GB) | 1986-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173037-A1 | Aminophenyl derivatives as selective androgen receptor modulators | AR, NR5A1, ESRRA | TDP1 2425/4885VCAM1 2045/4885TSHR 424/4885 |
| US-20090270449-A1 | AMINOPHENYL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | AR, NR5A1, ESRRA | TDP1 2425/4885VCAM1 2045/4885TSHR 424/4885 |
| US-20060160845-A1 | Aminophenyl derivatives as selective androgen receptor modulators | AR, NR5A1, ESRRA | TDP1 2425/4885VCAM1 2045/4885TSHR 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.