Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4477714 | 0.90 | RAB9A (0.53) | RAB9ASMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL7986364 | 0.76 | RAB9A (0.50) | RAB9ASMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL21835318 | 0.75 | APP (0.42) | RAB9ASMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL23653213 | 0.74 | RAB9A (0.66) | RAB9ASMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL16686955 | 0.73 | MAPT (0.43) | RAB9ASMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL21835406 | 0.72 | HRH3 (0.45) | RAB9AALDH1A1NPC1GAAPOLB | |
| SCHEMBL31191055 | 0.71 | RAB9A (0.57) | RAB9ASMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL3776760 | 0.70 | KDM4E (0.59) | RAB9ASMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL7986358 | 0.70 | BCL9 (0.54) | RAB9ASMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL16686872 | 0.70 | RAB9A (0.50) | RAB9ASMN1; SMN2ALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504412-B2 | Imidazopyridine derivatives | BANYU PHARMACEUTICALS, CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| US-20080200494-A1 | Imidazopyridine Derivatives | MSD K.K. (JP) | 2008-08-21 | — | — | US | disclosed |
| EP-1657242-A1 | IMIDAZOPYRIDINE DERIVATIVES | Banyu Pharmaceutical Co., Ltd. (JP) | 2006-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200494-A1 | Imidazopyridine Derivatives | MC1R, MC3R, MC5R | RAB9A 1979/4885SMN1; SMN2 2050/4885ALDH1A1 1277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.