Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465159 | 0.84 | HTR6 (0.44) | HTR6SIGMAR1KDM4EHTR2ALMNA | |
| SCHEMBL4462414 | 0.83 | HTR6 (0.38) | HTR6SIGMAR1KDM4EHTR2ALMNA | |
| Hydrochloric Acid SCHEMBL4472154 | 0.81 | HTR6 (0.39) | HTR6SIGMAR1KDM4EHTR2ALMNA | |
| SCHEMBL4464749 | 0.81 | HTR6 (0.41) | HTR6SIGMAR1KDM4EHTR2ALMNA | |
| SCHEMBL4460640 | 0.79 | HTR6 (0.40) | HTR6SIGMAR1KDM4EHTR2ALMNA | |
| SCHEMBL4463037 | 0.79 | HTR6 (0.42) | HTR6SIGMAR1KDM4EHTR2ALMNA | |
| Hydrochloric Acid SCHEMBL4459355 | 0.77 | HTR6 (0.43) | HTR6SIGMAR1KDM4EHTR2ALMNA | |
| Hydrochloric Acid SCHEMBL4472715 | 0.76 | HTR6 (0.40) | HTR6SIGMAR1KDM4EHTR2ALMNA | |
| SCHEMBL4466107 | 0.75 | HTR6 (0.39) | HTR6SIGMAR1KDM4EHTR2ALMNA | |
| SCHEMBL1452608 | 0.75 | HTR6 (0.41) | HTR6SIGMAR1KDM4EHTR2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1671983-B1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA SA (ES) | 2009-02-25 | — | — | EP | claimed |