SCHEMBL4470436

SCHEMBL4470436

CC(c1ccc(O)c(F)c1)(c1ccc(O)c(F)c1)c1ccc(O)c(F)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.52
ESR2 Q92731 5/20 0.52
ALDH1A1 P00352 2/20 0.46
ALOX15 P16050 2/20 0.46
HSD17B10 Q99714 2/20 0.46
HPGD P15428 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
RECQL P46063 1/20 0.42
KMT2A Q03164 1/20 0.42
ESRRG P62508 1/20 0.41
HSD17B1 P14061 3/20 0.40
HSD17B2 P37059 3/20 0.40
KLF10 Q13118 1/20 0.39
SHBG P04278 1/20 0.39
SNCA P37840 1/20 0.38
MGLL Q99685 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3690287 0.92 ESR1 (0.50) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL29874701 0.90 ESR1 (0.68) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL545282 0.90 ESR1 (0.68) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL179468 0.86 ALDH1A1 (0.64) ESR1ALDH1A1ALOX15HSD17B10HPGD
SCHEMBL30249992 0.86 ALDH1A1 (0.64) ESR1ALDH1A1ALOX15HSD17B10HPGD
SCHEMBL29372911 0.86 ESR1 (0.61) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL544510 0.86 ESR1 (0.61) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL4462227 0.84 ESR1 (0.59) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL3047260 0.84 ALDH1A1 (0.45) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL13416167 0.84 ESR1 (0.65) ESR1ESR2ALOX15HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6288204-B1 CONDENSATION POLYMERIZATION OF BISPHENOL A, TRIHYDRIC PHENOL, AND PHOSGENE; ADDING TETRAAMMONIUM SALT AND MONOHYDRIC PHENOL FOR MOLECULAR WEIGHT CONTROL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-09-11 US disclosed