Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965681 | 1.00 | EPHA2 (0.47) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL4635237 | 0.80 | DPP4 (0.47) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL4635925 | 0.79 | DPP4 (0.47) | CHRM4DPP4DPP9ADRA1BADRA1D | |
| SCHEMBL13783797 | 0.78 | F2RL1 (0.44) | ALDH1A1HTTLMNAKDM4EGAA | |
| SCHEMBL4539952 | 0.75 | ALDH1A1 (0.45) | ALDH1A1HTTLMNAKDM4EHPGD | |
| SCHEMBL19262544 | 0.74 | BPTF (0.44) | — | |
| SCHEMBL6926246 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HTTKDM4ECHRM4L3MBTL1 | |
| SCHEMBL4321196 | 0.73 | ALDH1A1 (0.48) | ALDH1A1HTTLMNAKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL3955678 | 0.73 | DPP4 (0.41) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL24018033 | 0.72 | CHRM4 (0.48) | EPHA2FLT4GSK3BRARBTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |