SCHEMBL447112

SCHEMBL447112

CCCCCCCCCCCCSC(N)=S.[Zn]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.46
NOS1 P29475 1/20 0.46
NOS2 P35228 1/20 0.46
EPHX1 P07099 1/20 0.42
CYP1A2 P05177 1/20 0.40
SPHK2 Q9NRA0 1/20 0.38
SPHK1 Q9NYA1 1/20 0.38
THRB P10828 2/20 0.38
HSD17B10 Q99714 2/20 0.38
CES2 O00748 1/20 0.38
CTSL P07711 1/20 0.38
CTSB P07858 1/20 0.38
GMNN O75496 1/20 0.38
TP53 P04637 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
BLM P54132 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27810232 1.00 NOS3 (0.46) NOS3NOS1NOS2EPHX1CYP1A2
SCHEMBL27695451 1.00 NOS3 (0.46) NOS3NOS1NOS2EPHX1CYP1A2
SCHEMBL27715507 1.00 NOS3 (0.46) NOS3NOS1NOS2EPHX1CYP1A2
SCHEMBL27614640 1.00 NOS3 (0.46) NOS3NOS1NOS2EPHX1CYP1A2
SCHEMBL21808792 1.00 NOS3 (0.46) NOS3NOS1NOS2EPHX1CYP1A2
SCHEMBL27950748 1.00 NOS3 (0.46) NOS3NOS1NOS2EPHX1CYP1A2
SCHEMBL28307913 1.00 NOS3 (0.46) NOS3NOS1NOS2EPHX1CYP1A2
SCHEMBL29282001 1.00 NOS3 (0.46) NOS3NOS1NOS2EPHX1CYP1A2
SCHEMBL2385796 0.98 NOS3 (0.48) NOS3NOS1NOS2EPHX1CYP1A2
SCHEMBL27722899 0.98 NOS3 (0.48) NOS3NOS1NOS2EPHX1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110494480-A Rubber composition, the manufacturing method of rubber composition and tire BRIDGESTONE CORP 2019-11-22 CN disclosed
CN-107428211-A Tire 株式会社普利司通 2017-12-01 CN disclosed
CN-107428212-A Tyre for vehicle wheels 株式会社普利司通 2017-12-01 CN disclosed
CN-106795295-A The manufacture method of rubber composition 株式会社普利司通 2017-05-31 CN disclosed
EP-2423253-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2014-04-30 EP disclosed
CN-102414269-B Rubber composition and pneumatic tire BRIDGESTONE CORP 2013-10-02 CN disclosed
CN-103189443-A Rubber composition and method of producing same, and tire BRIDGESTONE CORP 2013-07-03 CN disclosed
CN-101589100-B Rubber composition and tire using the same BRIDGESTONE CORP 2013-03-20 CN disclosed
CN-102414269-A Rubber composition and pneumatic tire BRIDGESTONE CORP 2012-04-11 CN disclosed
US-20120065325-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2012-03-15 US disclosed
EP-2423253-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2012-02-29 EP disclosed
CN-101107347-B Grease composition for hub unit bearing, and hub unit bearing for vehicles NSK LTD 2011-08-17 CN disclosed
CN-101589100-A Rubber combination and the tire that uses it BRIDGESTONE CORP (JP) 2009-11-25 CN disclosed
EP-1445277-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING THE SAME BRIDGESTONE CORP (JP) 2009-01-07 EP disclosed
CN-101107347-A Grease composition for hub unit bearing, and hub unit bearing for vehicles NSK LTD (JP) 2008-01-16 CN disclosed
US-7060757-B2 Rubber composition and pneumatic tire using the same BRIDGESTONE CORPORATION (JP) 2006-06-13 US disclosed
US-20040220351-A1 Rubber composition and pneumatic tire using the same BRIDGESTONE CORPORATION 2004-11-04 US disclosed
EP-1445277-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING THE SAME BRIDGESTONE CORPORATION (JP) 2004-08-11 EP disclosed